Mesna

Also known as: Sodium 2-mercaptoethanesulfonate, 2-Mercaptoethanesulfonic acid sodium salt, Coenzyme M sodium salt, Uromitexan, Mesnex, Sodium 2-sulfanylethanesulfonate, Mesna sodium salt, 2-Mercaptoethanesulfonic acid monosodium salt

Mesna (CAS 19767-45-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C2H5NaO3S2 and a molecular weight of 164.179 g/mol. Key property: a melting point of >240°C dec.. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Nov 3, 2026.

CAS No.: 19767-45-4
Jingsj CID: J-1959624-8
Molecular Formula: C₂H₅NaO₃S₂
Molecular Weight: 164.179 g/mol
Category: Organic Compounds
Last updated: 11/3/2026

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Physicochemical Properties

Melting Point	>240°C dec.
Exact Mass	163.957779
PSA	104.38000
LogP	0.54220
Stability	Stable. Incompatible with strong oxidizing agents.

GHS Safety & Compliance

IrritantSignal word: Warning

H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information	[1]. Yilmaz ER, Kertmen H, Gürer B, The protective effect of 2-mercaptoethane sulfonate (MESNA) against traumatic brain injury in rats. Acta Neurochir (Wien). 2013 Jan;155(1):141-9; discussion 149. [2]. Li X, Yang S, Lv X, The mechanism of mesna in protection from cisplatin-induced ovarian damage in female rats. J Gynecol Oncol. 2013 Apr;24(2):177-85. [3]. Gressier B; Cabanis A; Lebegue S; Antioxidant Activity of Mesna: Interest During Pulmonary Inflammatory Diseases. Pharm.Weekbl. Sci.Ed., 1992, 14, No. 5, Suppl. F, F48 [4]. Bogush TA, Smirnova GB, Chmutin EF, Effect of MESNA on intracellular accumulation of doxorubicin and its interaction with DNA. Antibiot Khimioter. 1994 Sep-Oct;39(9-10):30-5.

Additional Information

[1]. Yilmaz ER, Kertmen H, Gürer B, The protective effect of 2-mercaptoethane sulfonate (MESNA) against traumatic brain injury in rats. Acta Neurochir (Wien). 2013 Jan;155(1):141-9; discussion 149. [2]. Li X, Yang S, Lv X, The mechanism of mesna in protection from cisplatin-induced ovarian damage in female rats. J Gynecol Oncol. 2013 Apr;24(2):177-85. [3]. Gressier B; Cabanis A; Lebegue S; Antioxidant Activity of Mesna: Interest During Pulmonary Inflammatory Diseases. Pharm.Weekbl. Sci.Ed., 1992, 14, No. 5, Suppl. F, F48 [4]. Bogush TA, Smirnova GB, Chmutin EF, Effect of MESNA on intracellular accumulation of doxorubicin and its interaction with DNA. Antibiot Khimioter. 1994 Sep-Oct;39(9-10):30-5.

Customs & Trade Information

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Mesna?

The CAS number of Mesna is 19767-45-4.

What are the molecular formula and molecular weight of Mesna?

Mesna has molecular formula C2H5NaO3S2 and molecular weight 164.179 g/mol.

Is Mesna hazardous?

Mesna has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Mesna?

For Mesna, Upstream Products: Sodium 2-bromoethanesulfonate; Downstream Products: Coenzyme M, Perfosfamide.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 11/3/2026

How to cite: Jingsj. "Mesna (CAS 19767-45-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959624-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.