DMAT

Also known as: 2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole, 4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine, 4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzo[d]imidazol-2-amine, CK2 Inhibitor II, Casein Kinase II Inhibitor II, Casein Kinase II Inhibitor

DMAT (CAS 749234-11-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C9H7Br4N3 and a molecular weight of 476.78800 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 749234-11-5
Jingsj CID: J-1959461-5
Molecular Formula: C₉H₇Br₄N₃
Molecular Weight: 476.78800 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Exact Mass	472.73700
PSA	31.92000
LogP	4.67890
Storage Conditions	2-8℃

Activity & Biological Data

Target	CK2:0.13 μM (IC50, Human CK2) PIM1:0.148 μM (IC50) PIM2:1.6 μM (IC50) PIM3:0.097 μM (IC50) HIPK2:0.37 μM (IC50) HIPK3:0.59 μM (IC50) DYRK1a:0.41 μM (IC50) DYRK2:0.35 μM (IC50) DYRK3:1.7 μM (IC50) PKD1:0.18 μM (IC50) CDK2:0.64 μM (IC50)
Additional Information	[1]. Yde CW, et al. Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitorDMAT. Cancer Lett. 2007 Oct 28;256(2):229-37. [2]. Lawnicka H, et al. Anti-neoplastic effect of protein kinase CK2 inhibitor, 2-dimethylamino-4,5,6,7-tetrabromobenzimidazole (DMAT), on growth and hormonal activity of human adrenocortical carcinoma cell line (H295R) in vitro. Cell Tissue Res. 2010 May;340( [3]. Pagano MA, et al. The selectivity of inhibitors of protein kinase CK2: an update. Biochem J. 2008 Nov 1;415(3):353-65. [4]. Sass G, et al. Inhibition of experimental HCC growth in mice by use of the kinase inhibitor DMAT. Int J Oncol. 2011 Aug;39(2):433-42.

Target

CK2:0.13 μM (IC50, Human CK2) PIM1:0.148 μM (IC50) PIM2:1.6 μM (IC50) PIM3:0.097 μM (IC50) HIPK2:0.37 μM (IC50) HIPK3:0.59 μM (IC50) DYRK1a:0.41 μM (IC50) DYRK2:0.35 μM (IC50) DYRK3:1.7 μM (IC50) PKD1:0.18 μM (IC50) CDK2:0.64 μM (IC50)

Additional Information

[1]. Yde CW, et al. Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitorDMAT. Cancer Lett. 2007 Oct 28;256(2):229-37. [2]. Lawnicka H, et al. Anti-neoplastic effect of protein kinase CK2 inhibitor, 2-dimethylamino-4,5,6,7-tetrabromobenzimidazole (DMAT), on growth and hormonal activity of human adrenocortical carcinoma cell line (H295R) in vitro. Cell Tissue Res. 2010 May;340( [3]. Pagano MA, et al. The selectivity of inhibitors of protein kinase CK2: an update. Biochem J. 2008 Nov 1;415(3):353-65. [4]. Sass G, et al. Inhibition of experimental HCC growth in mice by use of the kinase inhibitor DMAT. Int J Oncol. 2011 Aug;39(2):433-42.

Frequently Asked Questions

What is the CAS number of DMAT?

The CAS number of DMAT is 749234-11-5.

What are the molecular formula and molecular weight of DMAT?

DMAT has molecular formula C9H7Br4N3 and molecular weight 476.78800 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "DMAT (CAS 749234-11-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959461-5 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.