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Cycleanine

Also known as: O,O'-Dimethylisochondodendrine, Dimethylisochondodendrine, (12aR,24aR)-5,6,17,18-tetramethoxy-1,13-dimethyl-2,3,12a,13,14,15,24,24a-octahydro-1H,12H-8,11:20,23-dietheno[1,10]dioxacyclooctadecino[13,12,11-ij:4,3,2-i'j']diisoquinoline, 6,7,6',7'-tetramethoxy-2,2'-dimethyl-cycleanane, 7,11-di-O-methylisochondodendrine

Cycleanine (CAS 518-94-5) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C38H42N2O6 and a molecular weight of 622.75 g/mol. Key properties include a boiling point of 691.6±55.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 169.8±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
518-94-5
Jingsj CID
J-1959315-3
Molecular Formula
C38H42N2O6
Molecular Weight
622.75 g/mol
Category
Organic Bases
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point691.6±55.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point169.8±28.7 °C
Exact Mass622.304260
PSA61.86000
LogP3.96
Vapor Pressure0.0±2.2 mmHg at 25°C
Refractive Index1.586

Activity & Biological Data

TargetL-type calcium channel
Additional Information[1]. Martínez JA, et al. Calcium antagonist properties of the bisbenzylisoquinoline alkaloid cycleanine. Fundam Clin Pharmacol. 1998;12(2):182-7. [2]. Uche FI, et al. Cytotoxicity Effects and Apoptosis Induction by Bisbenzylisoquinoline Alkaloids from Triclisia subcordata. Phytother Res. 2016 Sep;30(9):1533-9.

Frequently Asked Questions

What is the CAS number of Cycleanine?

The CAS number of Cycleanine is 518-94-5.

What are the molecular formula and molecular weight of Cycleanine?

Cycleanine has molecular formula C38H42N2O6 and molecular weight 622.75 g/mol.

What are the upstream and downstream products of Cycleanine?

For Cycleanine, Upstream Products: Diazomethane; Downstream Products: Armepavine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Cycleanine (CAS 518-94-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959315-3 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.