N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine
Also known as: PD 153035, AG 1517, ZM 252868, SU 5271, Tyrphostin AG 1517, 4-Quinazolinamine, N-(3-bromophenyl)-6,7-dimethoxy-, N-(3-bromophenyl)-6,7-dimethoxy-4-quinazolinamine, PD153035 HCl, Zinc00600292
N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine (CAS 153436-54-5) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C16H14BrN3O2 and a molecular weight of 360.205 g/mol. Key properties include a boiling point of 472.1±45.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 239.3±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 153436-54-5
- Jingsj CID
- J-1959098-8
- Molecular Formula
- C16H14BrN3O2
- Molecular Weight
- 360.205 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 472.1±45.0 °C at 760 mmHg |
|---|---|
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 239.3±28.7 °C |
| Exact Mass | 359.026947 |
| PSA | 56.27000 |
| LogP | 4.08 |
| Vapor Pressure | 0.0±1.2 mmHg at 25°C |
| Refractive Index | 1.679 |
| Storage Conditions | 2-8°C |
Activity & Biological Data
| Target | EGFR:6 pM (Ki) EGFR:25 pM (IC50) |
|---|---|
| Additional Information | [1]. Bridges AJ, et al. Tyrosine kinase inhibitors. 8. An unusually steep structure-activity relationship for analogues of 4-(3-bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a potent inhibitor of the epidermal growth factor receptor. J Med Chem. 1996 Jan 5;39(1):267-76. [2]. Fry DW, et al. A specific inhibitor of the epidermal growth factor receptor tyrosine kinase. Science. 1994 Aug 19;265(5175):1093-5. [3]. Bos M, et al. PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptoractivation and inhibits growth of cancer cells in a receptor number-dependent manner. Clin Cancer Res. 1997 Nov;3(11):2099-106. [4]. Kunkel MW, et al. Inhibition of the epidermal growth factor receptor tyrosine kinase by PD153035 in human A431 tumors in athymic nude mice. Invest New Drugs. 1996;13(4):295-302. |
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine?
The CAS number of N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine is 153436-54-5.
What are the molecular formula and molecular weight of N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine?
N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine has molecular formula C16H14BrN3O2 and molecular weight 360.205 g/mol.
What are the upstream and downstream products of N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine?
For N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine, Upstream Products: 3-Bromoaniline, 4-Chloro-6,7-dimethoxyquinazoline, 2-Amino-4,5-dimethoxybenzoic acid; Downstream Products: 4-((3-Bromophenyl)amino)quinazoline-6,7-diol.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine (CAS 153436-54-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959098-8 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.