Laquinimod

Also known as: ABR-215062, ABR 215062, ABR215062, TV-5600, TV5600, TV 5600, SAIK-MS, CIVENTICHEM CV-4057, CS-82, 5-chloro-N-ethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide, 5-chloro-4-hydroxy-1-methyl-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid ethyl-phenyl-amide, 5-chloro-N-ethyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-N-phenyl-3-quinolinecarboxamide, 5-chloro-N-ethyl-2-hydroxy-1-methyl-4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide, N-ethyl-N-phenyl-5-chloro-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-quinoline-3-carboxamide, Laquinimod (ABR-215062)

Laquinimod (CAS 248281-84-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C19H17ClN2O3 and a molecular weight of 356.80 g/mol. Key properties include a boiling point of 546.0±50.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 284.0±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 248281-84-7
Jingsj CID: J-1959092-2
Molecular Formula: C₁₉H₁₇ClN₂O₃
Molecular Weight: 356.80 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	546.0±50.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	284.0±30.1 °C
PSA	87.42000
LogP	2.79
Vapor Pressure	0.0±1.5 mmHg at 25°C
Refractive Index	1.587

Activity & Biological Data

Target	NF-κB
Additional Information	[1]. Schulze-Topphoff, Ulf., et al. Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity. PLoS One (2012), 7(3), e33797. [2]. Toubi E, et al. Laquinimod modulates B cells and their regulatory effects on T cells in Multiple Sclerosis. J Neuroimmunol. 2012 Oct 15;251(1-2):45-54. [3]. Brück W, et al. Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination. Acta Neuropathol. 2012 Sep;124(3):411-24.

Target

NF-κB

Additional Information

[1]. Schulze-Topphoff, Ulf., et al. Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity. PLoS One (2012), 7(3), e33797. [2]. Toubi E, et al. Laquinimod modulates B cells and their regulatory effects on T cells in Multiple Sclerosis. J Neuroimmunol. 2012 Oct 15;251(1-2):45-54. [3]. Brück W, et al. Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination. Acta Neuropathol. 2012 Sep;124(3):411-24.

Customs & Trade Information

HS Code	2933790090
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Laquinimod?

The CAS number of Laquinimod is 248281-84-7.

What are the molecular formula and molecular weight of Laquinimod?

Laquinimod has molecular formula C19H17ClN2O3 and molecular weight 356.80 g/mol.

What are the upstream and downstream products of Laquinimod?

For Laquinimod, Upstream Products: N-Ethylaniline, Methyl 5-chloro-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate, 5-Chloro-1H-benzo[d][1,3]oxazine-2,4-dione; Downstream Products: Methyl 5-chloro-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Laquinimod (CAS 248281-84-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959092-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.