Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate

Also known as: ITE, Methyl 2-(1H-indole-3-carbonyl)-1,3-thiazole-4-carboxylate, 2-(1H-Indol-3-ylcarbonyl)-4-thiazolecarboxylic acid methyl ester, ARYL HYDROCARBON RECEPTOR LIGAND, hms3268g16, 4-Thiazolecarboxylic acid, 2-(1H-indol-3-ylcarbonyl)-, methyl ester

Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate (CAS 448906-42-1) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C14H10N2O3S and a molecular weight of 286.30600 g/mol. Key properties include a boiling point of 520.4ºC at 760 mmHg, a density of 1.427g/cm3 and a flash point of 268.5ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 448906-42-1
Jingsj CID: J-1959016-1
Molecular Formula: C₁₄H₁₀N₂O₃S
Molecular Weight: 286.30600 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Boiling Point	520.4ºC at 760 mmHg
Density	1.427g/cm3
Flash Point	268.5ºC
Exact Mass	286.04100
PSA	100.29000
LogP	2.64200
Refractive Index	1.688
Storage Conditions	2-8℃

Activity & Biological Data

Target	Ki: 3 nM (AhR)[1]
Additional Information	[1]. Song J, et al. A ligand for the aryl hydrocarbon receptor isolated from lung. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14694-9. [2]. Nugent LF, et al. ITE, a novel endogenous nontoxic aryl hydrocarbon receptor ligand, efficiently suppresses EAU and T-cell-mediated immunity. Invest Ophthalmol Vis Sci. 2013 Nov 13;54(12):7463-9. [3]. Pang LP, et al. ITE inhibits growth of human pulmonary artery endothelial cells. Exp Lung Res. 2017 Oct;43(8):283-292.

Target

Ki: 3 nM (AhR)[1]

Additional Information

[1]. Song J, et al. A ligand for the aryl hydrocarbon receptor isolated from lung. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14694-9. [2]. Nugent LF, et al. ITE, a novel endogenous nontoxic aryl hydrocarbon receptor ligand, efficiently suppresses EAU and T-cell-mediated immunity. Invest Ophthalmol Vis Sci. 2013 Nov 13;54(12):7463-9. [3]. Pang LP, et al. ITE inhibits growth of human pulmonary artery endothelial cells. Exp Lung Res. 2017 Oct;43(8):283-292.

Customs & Trade Information

HS Code	2934100090
Summary	2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate?

The CAS number of Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate is 448906-42-1.

What are the molecular formula and molecular weight of Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate?

Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate has molecular formula C14H10N2O3S and molecular weight 286.30600 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate (CAS 448906-42-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959016-1 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.