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(±)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid

Also known as: (±)-CPP, (RS)-CPP, 3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid, 2-Piperazinecarboxylic acid, 4-(3-phosphonopropyl)-, (R,S)-CPP, DL-CPP, 3-2-Cpp, (+/-)-CPP, CPP, NMDA antagonist

(±)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid (CAS 100828-16-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C8H17N2O5P and a molecular weight of 252.20 g/mol. Key properties include a boiling point of 546.7ºC at 760mmHg, a density of 1.408g/cm3 and a flash point of 284.4ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
100828-16-8
Jingsj CID
J-1959013-8
Molecular Formula
C8H17N2O5P
Molecular Weight
252.20 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point546.7ºC at 760mmHg
Density1.408g/cm3
Flash Point284.4ºC
Exact Mass252.08800
PSA119.91000
Vapor Pressure2.14E-13mmHg at 25°C
Refractive Index1.53

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. J Davies, et al. CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity. Brain Res. 1986 Sep 10;382(1):169-73.

Frequently Asked Questions

What is the CAS number of (±)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid?

The CAS number of (±)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid is 100828-16-8.

What are the molecular formula and molecular weight of (±)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid?

(±)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid has molecular formula C8H17N2O5P and molecular weight 252.20 g/mol.

Is (±)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid hazardous?

(±)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of (±)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid?

For (±)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid, Upstream Products: 2-Piperazinecarboxylic acid, Pyrazinamide, ethyl 2-piperazinecarboxylate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "(±)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid (CAS 100828-16-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959013-8 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.