Avasimibe

Also known as: 2,6-diisopropylphenyl [(2,4,6-triisopropylphenyl)acetyl]sulfamate, 2,6-di(propan-2-yl)phenyl {[2,4,6-tri(propan-2-yl)phenyl]acetyl}sulfamate, N-[(2,6-DIISOPROPYLPHENOXY)SULFONYL]-2-(2,4,6-TRIISOPROPYLPHENYL)ACETAMIDE, CI-1011, PD 148515, Sulfamic acid, N-[2-[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl ester, [2,6-di(propan-2-yl)phenyl] N-[2-[2,4,6-tri(propan-2-yl)phenyl]acetyl]sulfamate, 1-[(2,6-DIISOPROPYLPHENOXYSULFONYL)AMINO]-2-(2,4,6-TRIISOPROPYLPHENYL)ETHANONE

Avasimibe (CAS 166518-60-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C29H43NO4S and a molecular weight of 501.721 g/mol. Key properties include a melting point of 178-180° (Lee); mp 169.5-170.4° (Dozeman) and a density of 1.1±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 166518-60-1
Jingsj CID: J-1958913-0
Molecular Formula: C₂₉H₄₃NO₄S
Molecular Weight: 501.721 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	178-180° (Lee); mp 169.5-170.4° (Dozeman)
Density	1.1±0.1 g/cm3
Exact Mass	501.291290
PSA	80.85000
LogP	9.34
Appearance	white to tan
Refractive Index	1.529
Storage Conditions	room temp
Additional Property	DMSO: ≥40mg/mL

Activity & Biological Data

Additional Information	[1]. Tardif JC et al. Effects of the acyl coenzyme A:cholesterol acyltransferase inhibitor avasimibe on human atherosclerotic lesions. Circulation, 2004 Nov 23, 110(21):3372-7. [2]. Raal FJ et al. Avasimibe, an ACAT inhibitor, enhances the lipid lowering effect of atorvastatin in subjects with homozygousfamilial hypercholesterolemia. Atherosclerosis, 2003 Dec, 171(2):273-9. [3]. Delsing DJ et al. Acyl-CoA:cholesterol acyltransferase inhibitor avasimibe reduces atherosclerosis in addition to its cholesterol-lowering effect in ApoE*3-Leiden mice. Circulation, 2001 Apr 3, 103(13):1778-86.

Additional Information

[1]. Tardif JC et al. Effects of the acyl coenzyme A:cholesterol acyltransferase inhibitor avasimibe on human atherosclerotic lesions. Circulation, 2004 Nov 23, 110(21):3372-7. [2]. Raal FJ et al. Avasimibe, an ACAT inhibitor, enhances the lipid lowering effect of atorvastatin in subjects with homozygousfamilial hypercholesterolemia. Atherosclerosis, 2003 Dec, 171(2):273-9. [3]. Delsing DJ et al. Acyl-CoA:cholesterol acyltransferase inhibitor avasimibe reduces atherosclerosis in addition to its cholesterol-lowering effect in ApoE*3-Leiden mice. Circulation, 2001 Apr 3, 103(13):1778-86.

Customs & Trade Information

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Frequently Asked Questions

What is the CAS number of Avasimibe?

The CAS number of Avasimibe is 166518-60-1.

What are the molecular formula and molecular weight of Avasimibe?

Avasimibe has molecular formula C29H43NO4S and molecular weight 501.721 g/mol.

What are the upstream and downstream products of Avasimibe?

For Avasimibe, Upstream Products: 2,4,6-Triisopropylbenzoyl chloride, 2,4,6-Triisopropylphenylacetic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Avasimibe (CAS 166518-60-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1958913-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.