Silodosin

Also known as: 1-(3-Hydroxypropyl)-5-[(2R)-2-({2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]-2,3-dihydro-1H-indole-7-carboxamide, 1-(3-Hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-2,3-dihydro-1H-indole-7-carboxamide, Rapaflo, Urief, KMD-3213, KAD 3213, Silodyx, Silodoxin, UNII-CUZ39LUY82, 1H-Indole-7-carboxamide, 2,3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-

Silodosin (CAS 160970-54-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C25H32F3N3O4 and a molecular weight of 495.534 g/mol. Key properties include a melting point of 107 °C, a boiling point of 601.4±55.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 317.5±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 160970-54-7
Jingsj CID: J-1958723-6
Molecular Formula: C₂₅H₃₂F₃N₃O₄
Molecular Weight: 495.534 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	107 °C
Boiling Point	601.4±55.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	317.5±31.5 °C
Exact Mass	495.234497
PSA	97.05000
LogP	2.52
Vapor Pressure	0.0±1.8 mmHg at 25°C
Refractive Index	1.552

Activity & Biological Data

Additional Information	[1]. Kobayashi, Shinya; Tomiyama, Yoshitaka; Effects of silodosin and tamsulosin on the urethra and cardiovascular system in young and old dogs with benign prostatic hyperplasia. European Journal of Pharmacology (2009), 613(1-3), 135-140. [2]. Tatemichi, Satoshi; Tomiyama, Yoshitaka; Maruyama, Itaru; Uroselectivity in male dogs of silodosin (KMD-3213), a novel drug for the obstructive component of benign prostatic hyperplasia. Neurourology and Urodynamics (2006), 25(7), 792-794. [3]. Osman NI, Chapple CR, Cruz F, Desgrandchamps F, Llorente C, Montorsi F.Silodosin : a new subtype selective alpha-1 antagonist for the treatment of lower urinary tract symptoms in patients with benign prostatic hyperplasia.Expert Opin Pharmacother. 2012 Oc [4]. Cui Y, Zong H, Zhang Y.The efficacy and safety of silodosin in treating BPH: a systematic review and meta-analysis.Int Urol Nephrol. 2012 Aug 24. [5]. Goseki T, Ishikawa H, Ogasawara S, Mashimo K, Nemoto N, Taguchi Y, Yago K, Shimizu K.Effects of tamsulosin and silodosin on isolated albino and pigmented rabbit iris dilators: Possible mechanism of intraoperative floppy-iris syndrome.J Cataract Refract Su

Additional Information

[1]. Kobayashi, Shinya; Tomiyama, Yoshitaka; Effects of silodosin and tamsulosin on the urethra and cardiovascular system in young and old dogs with benign prostatic hyperplasia. European Journal of Pharmacology (2009), 613(1-3), 135-140. [2]. Tatemichi, Satoshi; Tomiyama, Yoshitaka; Maruyama, Itaru; Uroselectivity in male dogs of silodosin (KMD-3213), a novel drug for the obstructive component of benign prostatic hyperplasia. Neurourology and Urodynamics (2006), 25(7), 792-794. [3]. Osman NI, Chapple CR, Cruz F, Desgrandchamps F, Llorente C, Montorsi F.Silodosin : a new subtype selective alpha-1 antagonist for the treatment of lower urinary tract symptoms in patients with benign prostatic hyperplasia.Expert Opin Pharmacother. 2012 Oc [4]. Cui Y, Zong H, Zhang Y.The efficacy and safety of silodosin in treating BPH: a systematic review and meta-analysis.Int Urol Nephrol. 2012 Aug 24. [5]. Goseki T, Ishikawa H, Ogasawara S, Mashimo K, Nemoto N, Taguchi Y, Yago K, Shimizu K.Effects of tamsulosin and silodosin on isolated albino and pigmented rabbit iris dilators: Possible mechanism of intraoperative floppy-iris syndrome.J Cataract Refract Su

Frequently Asked Questions

What is the CAS number of Silodosin?

The CAS number of Silodosin is 160970-54-7.

What are the molecular formula and molecular weight of Silodosin?

Silodosin has molecular formula C25H32F3N3O4 and molecular weight 495.534 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Silodosin (CAS 160970-54-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1958723-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.