Intepirdine

Also known as: SB-742457, SB 742457, GSK-742457, GSK 742457, RVT-101, 3-(Phenylsulfonyl)-8-(1-piperazinyl)quinoline, 3-(benzenesulfonyl)-8-piperazin-1-ylquinoline

Intepirdine (CAS 607742-69-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C19H19N3O2S and a molecular weight of 353.438 g/mol. Key properties include a boiling point of 608.3±45.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 321.7±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 607742-69-8
Jingsj CID: J-1958594-5
Molecular Formula: C₁₉H₁₉N₃O₂S
Molecular Weight: 353.438 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	608.3±45.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	321.7±28.7 °C
Exact Mass	353.119812
PSA	70.68000
LogP	2.10
Vapor Pressure	0.0±1.7 mmHg at 25°C
Refractive Index	1.649
Storage Conditions	-20℃

Activity & Biological Data

Additional Information	[1]. Callaghan CK, Hok V, Della-Chiesa A, et al. Age-related declines in delayed non-match-to-sample performance (DNMS) are reversed by the novel 5HT6 receptor antagonist SB742457. Neuropharmacology. 2012 Oct;63(5):890-7. [2]. Codony X, Vela JM, Ramírez MJ. 5-HT(6) receptor and cognition. Curr Opin Pharmacol. 2011 Feb;11(1):94-100. [3]. Maher-Edwards G, Dixon R, Hunter J, et al. SB-742457 and donepezil in Alzheimer disease: a randomized, placebo-controlled study. Int J Geriatr Psychiatry. 2011 May;26(5):536-44. [4]. Maher-Edwards G, Zvartau-Hind M, Hunter AJ, et al. Double-blind, controlled phase II study of a 5-HT6 receptor antagonist, SB-742457, in Alzheimer's disease. Curr Alzheimer Res. 2010 Aug;7(5):374-85. [5]. Upton N, Chuang TT, Hunter AJ, Virley DJ. 5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease. Neurotherapeutics. 2008 Jul;5(3):458-69. [6]. SB-742457

Additional Information

[1]. Callaghan CK, Hok V, Della-Chiesa A, et al. Age-related declines in delayed non-match-to-sample performance (DNMS) are reversed by the novel 5HT6 receptor antagonist SB742457. Neuropharmacology. 2012 Oct;63(5):890-7. [2]. Codony X, Vela JM, Ramírez MJ. 5-HT(6) receptor and cognition. Curr Opin Pharmacol. 2011 Feb;11(1):94-100. [3]. Maher-Edwards G, Dixon R, Hunter J, et al. SB-742457 and donepezil in Alzheimer disease: a randomized, placebo-controlled study. Int J Geriatr Psychiatry. 2011 May;26(5):536-44. [4]. Maher-Edwards G, Zvartau-Hind M, Hunter AJ, et al. Double-blind, controlled phase II study of a 5-HT6 receptor antagonist, SB-742457, in Alzheimer's disease. Curr Alzheimer Res. 2010 Aug;7(5):374-85. [5]. Upton N, Chuang TT, Hunter AJ, Virley DJ. 5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease. Neurotherapeutics. 2008 Jul;5(3):458-69. [6]. SB-742457

Frequently Asked Questions

What is the CAS number of Intepirdine?

The CAS number of Intepirdine is 607742-69-8.

What are the molecular formula and molecular weight of Intepirdine?

Intepirdine has molecular formula C19H19N3O2S and molecular weight 353.438 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Intepirdine (CAS 607742-69-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1958594-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.