Pilaralisib (XL147)

Also known as: 2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide, 2-amino-N-[3-[[3-(2-chloro-5-methoxyanilino)quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide, PILARALISIB, PILARALISIB (XL147), Pilaralisib (XL-147), SAR 245408, SAR-245408, SAR245408, XL 147, XL-147, XL-147,Pilaralisib, SAR245408, XL147, XL147(pilaralisib), pilaralisib, unii-60es45ktmk

Pilaralisib (XL147) (CAS 934526-89-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C25H25ClN6O4S and a molecular weight of 541.02200 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 934526-89-3
Jingsj CID: J-1958573-0
Molecular Formula: C₂₅H₂₅ClN₆O₄S
Molecular Weight: 541.02200 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Exact Mass	540.13500
PSA	166.66000
LogP	5.78640
Storage Conditions	-20°C

Activity & Biological Data

Target	PI3Kα:39 nM (IC50) PI3Kβ:383 nM (IC50) PI3Kδ:36 nM (IC50) PI3Kγ:23 nM (IC50) Vps34:6974 nM (IC50) DNA-PK:4750 nM (IC50)
Additional Information	[1]. Foster P, et al. The Selective PI3K Inhibitor XL147 (SAR245408) Inhibits Tumor Growth and Survival and Potentiates the Activity of Chemotherapeutic Agents in Preclinical Tumor Models. Mol Cancer Ther. 2015 Apr;14(4):931-40.

Frequently Asked Questions

What is the CAS number of Pilaralisib (XL147)?

The CAS number of Pilaralisib (XL147) is 934526-89-3.

What are the molecular formula and molecular weight of Pilaralisib (XL147)?

Pilaralisib (XL147) has molecular formula C25H25ClN6O4S and molecular weight 541.02200 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Pilaralisib (XL147) (CAS 934526-89-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1958573-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.