Aurora A Inhibitor I
Also known as: TC-S 7010, Aurora A-IN-10, Aurora-A Inhibitor I, N-(2-Chlorophenyl)-4-((2-((4-(2-(4-ethylpiperazin-1-yl)-2-oxoethyl)phenyl)amino)-5-fluoropyrimidin-4-yl)amino)benzamide, N-(2-chlorophenyl)-4-[[2-[[4-[2-(4-ethyl-1-piperazinyl)-2-oxoethyl]phenyl]amino]-5-fluoro-4-pyrimidinyl]amino]benzamide, Benzamide, N-(2-chlorophenyl)-4-[[2-[[4-[2-(4-ethyl-1-piperazinyl)-2-oxoethyl]phenyl]amino]-5-fluoro-4-pyrimidinyl]amino]-
Aurora A Inhibitor I (CAS 1158838-45-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C31H31ClFN7O2 and a molecular weight of 588.075 g/mol. Key property: a density of 1.4±0.1 g/cm3. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 1158838-45-9
- Jingsj CID
- J-1958253-7
- Molecular Formula
- C31H31ClFN7O2
- Molecular Weight
- 588.075 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Exact Mass | 587.221191 |
| PSA | 102.49000 |
| LogP | 4.39 |
| Appearance | white to beige |
| Refractive Index | 1.679 |
| Storage Conditions | 2-8°C |
| Additional Property | DMSO: soluble10mg/mL, clear |
GHS Safety & Compliance
- H302 — Harmful if swallowed
Activity & Biological Data
| Target | Aurora A:3.4 nM (IC50) Aurora B:3.4 μM (IC50) |
|---|---|
| Additional Information | [1]. Aliagas-Martin I, Burdick D, Corson L, Dotson J, Drummond J, Fields C, Huang OW, Hunsaker T, Kleinheinz T, Krueger E, Liang J, Moffat J, Phillips G, Pulk R, Rawson TE, Ultsch M, Walker L, Wiesmann C, Zhang B, Zhu BY, Cochran AG.A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.J Med Chem. 2009 May 28;52(10):3300-7. |
Frequently Asked Questions
What is the CAS number of Aurora A Inhibitor I?
The CAS number of Aurora A Inhibitor I is 1158838-45-9.
What are the molecular formula and molecular weight of Aurora A Inhibitor I?
Aurora A Inhibitor I has molecular formula C31H31ClFN7O2 and molecular weight 588.075 g/mol.
Is Aurora A Inhibitor I hazardous?
Aurora A Inhibitor I has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.
What are the upstream and downstream products of Aurora A Inhibitor I?
For Aurora A Inhibitor I, Upstream Products: 1-Ethylpiperazine, 4-[[4-[[4-[[(2-Chlorophenyl)amino]carbonyl]phenyl]amino]-5-fluoro-2-pyrimidinyl]amino]benzeneacetic acid.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Aurora A Inhibitor I (CAS 1158838-45-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1958253-7 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.