Tolmetin sodium

Also known as: Tolectin, Sodium tolmetin, sodium 1-methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetate, sodium 2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetate, 1-Methyl-5-(p-toluoyl)-1H-pyrrole-2-acetic acid sodium salt, Tolmetin sodium anhydrous, 1-Methyl-5-p-toluoyl-1H-pyrrole-2-acetic acid sodium salt

Tolmetin sodium (CAS 35711-34-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C15H14NNaO3 and a molecular weight of 279.26600 g/mol. Key properties include a melting point of 155-157ºC (DECOMPOSES), a boiling point of 483.2ºC at 760 mmHg, a density of 1.18g/cm3 and a flash point of 246ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 35711-34-3
Jingsj CID: J-1957881-5
Molecular Formula: C₁₅H₁₄NNaO₃
Molecular Weight: 279.26600 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	155-157ºC (DECOMPOSES)
Boiling Point	483.2ºC at 760 mmHg
Density	1.18g/cm3
Flash Point	246ºC
Exact Mass	279.08700
PSA	62.13000
LogP	0.85690

Activity & Biological Data

Target	Human COX-1:0.35 μM (IC50) Human COX-2:0.82 μM (IC50)
Additional Information	[1]. T D Warner, et al. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7563-8. [2]. Etcheverry SB, et al. Three new vanadyl(IV) complexes with non-steroidal anti-inflammatory drugs (Ibuprofen, Naproxen and Tolmetin). Bioactivity on osteoblast-like cells in culture. J Inorg Biochem. 2002 Jan 1;88(1):94-100. [3]. DADAŞ, Yakup, et al. Synthesis and anticancer activity of some novel tolmetin thiosemicarbazides. Marmara Pharmaceutical Journal 19(3) • April 2015

Target

Human COX-1:0.35 μM (IC50) Human COX-2:0.82 μM (IC50)

Additional Information

[1]. T D Warner, et al. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7563-8. [2]. Etcheverry SB, et al. Three new vanadyl(IV) complexes with non-steroidal anti-inflammatory drugs (Ibuprofen, Naproxen and Tolmetin). Bioactivity on osteoblast-like cells in culture. J Inorg Biochem. 2002 Jan 1;88(1):94-100. [3]. DADAŞ, Yakup, et al. Synthesis and anticancer activity of some novel tolmetin thiosemicarbazides. Marmara Pharmaceutical Journal 19(3) • April 2015

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Tolmetin sodium?

The CAS number of Tolmetin sodium is 35711-34-3.

What are the molecular formula and molecular weight of Tolmetin sodium?

Tolmetin sodium has molecular formula C15H14NNaO3 and molecular weight 279.26600 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Tolmetin sodium (CAS 35711-34-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1957881-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.