Monomethyl auristatin E

一甲基澳瑞他汀E

Also known as: MMAE, N-Methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide, N-Methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide, Vedotin, UNII-V7I58RC5EJ, Monomethylauristatin E

Monomethyl auristatin E (CAS 474645-27-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C39H67N5O7 and a molecular weight of 717.979 g/mol. It is also known as MMAE, N-Methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide and N-Methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. Key properties include a boiling point of 873.5±65.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 482.1±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.

474645-27-7

Jingsj CID

J-1957834-7

Molecular Formula

C₃₉H₆₇N₅O₇

Chinese Name

一甲基澳瑞他汀E

Molecular Weight

717.979 g/mol

Category

Organic Compounds

Last updated

8/21/2026