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Handelin

Also known as: handelin, Yejuhualactone, Yejuhua lactone, 6,6'-dihydroxy-6,6',9,9'-tetramethyl-3'-methylene-2,2'-dioxo-2',3a,3',3a',4,5,5',6,6a,6',7,9a,9b,9',9a',9b'-hexadecahydro-4'H-spiro[azuleno[4,5-b]furan-3,10'-[6a,9]ethanoazuleno[4,5-b]furan]-5-yl acetate, Spiro[azuleno[4,5-b]furan-3(2H),10'-[4H-6a,9]ethanoazuleno[4,5-b]furan]-2,2'(3'H)-dione, 4-(acetyloxy)-3a,3'a,4,5,5',6,6',6a,7,9',9a,9'a,9b,9'b-tetradecahydro-6,6'-dihydroxy-6,6',9,9'-tetramethyl-3'-methylene-, (3R,3aR,3'aS,4S,6R,6'R,6aR,6'aR,9'R,9aR,9'aS,9bR,9'bS)-

Handelin (CAS 62687-22-3) is a compound in the Esters category listed in the Jingsj chemical database. It has the molecular formula C32H40O8 and a molecular weight of 552.655 g/mol. Key properties include a boiling point of 731.0±60.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 236.3±26.4 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
62687-22-3
Jingsj CID
J-1957653-6
Molecular Formula
C32H40O8
Molecular Weight
552.655 g/mol
Category
Esters
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point731.0±60.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point236.3±26.4 °C
Exact Mass552.272339
PSA119.36000
LogP2.36
Vapor Pressure0.0±5.4 mmHg at 25°C
Refractive Index1.615

Activity & Biological Data

Additional Information[1]. Y Pyee, et al. Suppression of inflammatory responses by handelin, a guaianolide dimer from Chrysanthemum boreale, via downregulation of NF-κB signaling and pro-inflammatory cytokine production. J Nat Prod. 2014 Apr 25;77(4):917-24.

Frequently Asked Questions

What is the CAS number of Handelin?

The CAS number of Handelin is 62687-22-3.

What are the molecular formula and molecular weight of Handelin?

Handelin has molecular formula C32H40O8 and molecular weight 552.655 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Handelin (CAS 62687-22-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1957653-6 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.