Asunaprevir

Also known as: BMS-650032, BMS 650032, BMS650032, UNII-S9X0KRJ00S, tert-butyl (S)-1-((2S,4R)-4-(7-chloro-4-methoxyisoquinolin-1-yloxy)-2-((1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-vinylcyclopropylcarbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-ylcarbamate, 3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-[(7-chloro-4-methoxy-1-isoquinolinyl)oxy]-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-vinylcyclopropyl}-L-prolinamide

Asunaprevir (CAS 630420-16-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C35H46ClN5O9S and a molecular weight of 748.286 g/mol. Key property: a density of 1.4±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 630420-16-5
Jingsj CID: J-1957467-5
Molecular Formula: C₃₅H₄₆ClN₅O₉S
Molecular Weight: 748.286 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Density	1.4±0.1 g/cm3
Exact Mass	747.270447
PSA	201.18000
LogP	4.02
Refractive Index	1.616
Storage Conditions	2-8°C

Activity & Biological Data

Target	IC50: 0.2 nM-3.5 nM (HCV NS3 protease)
Additional Information	[1]. Pelosi LA, et al. Effect on HCV Replication by Combinations of Direct Acting Antivirals Including NS5A Inhibitor Daclatasvir.Antimicrob Agents Chemother. 2012 Jul 30. [2]. McPhee F, et al. Preclinical Profile and Characterization of the Hepatitis C Virus NS3 Protease Inhibitor Asunaprevir (BMS-650032).Antimicrob Agents Chemother. 2012 Aug 6. [3]. McPhee F, et al. Resistance analysis of the hepatitis C virus NS3 protease inhibitor asunaprevir.Antimicrob Agents Chemother. 2012 Jul;56(7):3670-81. [4]. Pasquinelli C, et al. Single- and multiple-ascending-dose studies of the NS3 protease inhibitor asunaprevir in subjects with or without chronic hepatitis C. Antimicrob Agents Chemother. 2012 Apr;56(4):1838-44.

Target

IC50: 0.2 nM-3.5 nM (HCV NS3 protease)

Additional Information

[1]. Pelosi LA, et al. Effect on HCV Replication by Combinations of Direct Acting Antivirals Including NS5A Inhibitor Daclatasvir.Antimicrob Agents Chemother. 2012 Jul 30. [2]. McPhee F, et al. Preclinical Profile and Characterization of the Hepatitis C Virus NS3 Protease Inhibitor Asunaprevir (BMS-650032).Antimicrob Agents Chemother. 2012 Aug 6. [3]. McPhee F, et al. Resistance analysis of the hepatitis C virus NS3 protease inhibitor asunaprevir.Antimicrob Agents Chemother. 2012 Jul;56(7):3670-81. [4]. Pasquinelli C, et al. Single- and multiple-ascending-dose studies of the NS3 protease inhibitor asunaprevir in subjects with or without chronic hepatitis C. Antimicrob Agents Chemother. 2012 Apr;56(4):1838-44.

Frequently Asked Questions

What is the CAS number of Asunaprevir?

The CAS number of Asunaprevir is 630420-16-5.

What are the molecular formula and molecular weight of Asunaprevir?

Asunaprevir has molecular formula C35H46ClN5O9S and molecular weight 748.286 g/mol.

What are the upstream and downstream products of Asunaprevir?

For Asunaprevir, Upstream Products: Boc-L-tert-leucine, 1,7-dichloro-4-methoxyisoquinoline, 4-Chlorocinnamic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Asunaprevir (CAS 630420-16-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1957467-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.