(R)-Baclofen

Also known as: (R)-Baclofen, Arbaclofen, (-)-Baclofen, (3R)-4-Amino-3-(4-chlorophenyl)butanoic acid, (3R)-4-Amino-3-(4-chlorophenyl)butyric acid, (R)-(-)-4-Amino-3-(4-chlorophenyl)butanoic acid, (R)-(-)-4-Amino-3-(4-chlorophenyl)butyric acid, (R)-(-)-Baclofen, (R)-4-Amino-3-(4-chlorophenyl)butanoic acid, (βR)-β-(Aminomethyl)-4-chlorobenzenepropanoic acid, Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, (βR)-

(R)-Baclofen (CAS 69308-37-8) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C10H12ClNO2 and a molecular weight of 213.661 g/mol. Key properties include a melting point of 171-174°C, a boiling point of 364.3±32.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 174.1±25.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 69308-37-8
Jingsj CID: J-1957375-2
Molecular Formula: C₁₀H₁₂ClNO₂
Molecular Weight: 213.661 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	171-174°C
Boiling Point	364.3±32.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	174.1±25.1 °C
Exact Mass	213.055649
PSA	63.32000
LogP	1.56
Vapor Pressure	0.0±0.9 mmHg at 25°C
Refractive Index	1.577
Storage Conditions	Store at RT

Activity & Biological Data

Additional Information	[1]. Falch E, Hedegaard A, Nielsen L et al. Comparative stereostructure-activity studies on GABAA and GABAB receptor sites and GABA uptake using rat brain membrane preparations. J Neurochem. 1986 Sep;47(3):898-903. [2]. Hong YG, Henry JL. Effects of phaclofen and the enantiomers of baclofen on cardiovascular responses to intrathecal administration of L- and D-baclofen in the rat. Eur J Pharmacol. 1991 Apr 24;196(3):267-75. [3]. Orsnes G, Crone C, Krarup C et al. The effect of baclofen on the transmission in spinal pathways in spastic multiple sclerosis patients. Clin Neurophysiol. 2000 Aug;111(8):1372-9. [4]. Colombo G, Addolorato G, Agabio R et al. Role of GABA(B) receptor in alcohol dependence: reducing effect of baclofen on alcohol intake and alcohol motivational properties in rats and amelioration of alcohol withdrawal syndrome and alcohol craving in human alcoholics. Neurotox Res. 2004;6(5):403-14. [5]. Stetkarova I, Yablon SA, Kofler M, Stokic DS. Procedure- and device-related complications of intrathecal baclofen administration for management of adult muscle hypertonia: a review. Neurorehabil Neural Repair. 2010 Sep;24(7):609-19.

Additional Information

[1]. Falch E, Hedegaard A, Nielsen L et al. Comparative stereostructure-activity studies on GABAA and GABAB receptor sites and GABA uptake using rat brain membrane preparations. J Neurochem. 1986 Sep;47(3):898-903. [2]. Hong YG, Henry JL. Effects of phaclofen and the enantiomers of baclofen on cardiovascular responses to intrathecal administration of L- and D-baclofen in the rat. Eur J Pharmacol. 1991 Apr 24;196(3):267-75. [3]. Orsnes G, Crone C, Krarup C et al. The effect of baclofen on the transmission in spinal pathways in spastic multiple sclerosis patients. Clin Neurophysiol. 2000 Aug;111(8):1372-9. [4]. Colombo G, Addolorato G, Agabio R et al. Role of GABA(B) receptor in alcohol dependence: reducing effect of baclofen on alcohol intake and alcohol motivational properties in rats and amelioration of alcohol withdrawal syndrome and alcohol craving in human alcoholics. Neurotox Res. 2004;6(5):403-14. [5]. Stetkarova I, Yablon SA, Kofler M, Stokic DS. Procedure- and device-related complications of intrathecal baclofen administration for management of adult muscle hypertonia: a review. Neurorehabil Neural Repair. 2010 Sep;24(7):609-19.

Frequently Asked Questions

What is the CAS number of (R)-Baclofen?

The CAS number of (R)-Baclofen is 69308-37-8.

What are the molecular formula and molecular weight of (R)-Baclofen?

(R)-Baclofen has molecular formula C10H12ClNO2 and molecular weight 213.661 g/mol.

What are the upstream and downstream products of (R)-Baclofen?

For (R)-Baclofen, Upstream Products: (R)-Baclofen hydrochloride, 4-Chlorobenzaldehyde.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "(R)-Baclofen (CAS 69308-37-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1957375-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.