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N-Fmoc-trans-4-hydroxy-L-proline methyl ester

Also known as: (2S,4R)-1-((9H-Fluoren-9-yl)methyl) 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate, 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(9H-fluoren-9-ylmethyl) 2-methyl ester, (2S,4R)-, 1-O-(9H-fluoren-9-ylmethyl) 2-O-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate, Fmoc-(2S,4R)-4-hydroxyproline methyl ester, Fmoc-Hyp-OMe, trans-Methyl N-Fmoc-4-hydroxy-L-prolinate

N-Fmoc-trans-4-hydroxy-L-proline methyl ester (CAS 122350-59-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C21H21NO5 and a molecular weight of 367.39500 g/mol. Key properties include a boiling point of 539.04ºC at 760 mmHg, a density of 1.329g/cm3 and a flash point of 279.801ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
122350-59-8
Jingsj CID
J-1957132-5
Molecular Formula
C21H21NO5
Molecular Weight
367.39500 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point539.04ºC at 760 mmHg
Density1.329g/cm3
Flash Point279.801ºC
Exact Mass367.14200
PSA76.07000
LogP2.48160
Vapor Pressure0mmHg at 25°C
Refractive Index1.622

Activity & Biological Data

Additional Information[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Customs & Trade Information

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of N-Fmoc-trans-4-hydroxy-L-proline methyl ester?

The CAS number of N-Fmoc-trans-4-hydroxy-L-proline methyl ester is 122350-59-8.

What are the molecular formula and molecular weight of N-Fmoc-trans-4-hydroxy-L-proline methyl ester?

N-Fmoc-trans-4-hydroxy-L-proline methyl ester has molecular formula C21H21NO5 and molecular weight 367.39500 g/mol.

What are the upstream and downstream products of N-Fmoc-trans-4-hydroxy-L-proline methyl ester?

For N-Fmoc-trans-4-hydroxy-L-proline methyl ester, Upstream Products: L-4-Hydroxyproline methyl ester hydrochloride, Fmoc-OSu, methyl (2S,4R)-4-hydroxypyrrolidine-2-carboxylate; Downstream Products: (2S,4R)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]-4-({[2-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)ethyl]carbamoyl}oxy)pyrrolidine-2-carboxylic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "N-Fmoc-trans-4-hydroxy-L-proline methyl ester (CAS 122350-59-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1957132-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.