Zatebradine

Also known as: Zatebradine [INN], UL-FS-49, UL-FS-49 free base, UL-FS-49CL free base, Zatebradina, Zatebradinum, 3-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one, 3-(3-((3,4-dimethoxyphenethyl)(methyl)amino)propyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one, 3-[3-[(3,4-dimethoxyphenethyl)methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one, 2H-3-Benzazepin-2-one, 3-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-, [14C]-Zatebradine

Zatebradine (CAS 85175-67-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C26H36N2O5 and a molecular weight of 456.57400 g/mol. Key properties include a boiling point of 612.5ºC at 760 mmHg, a density of 1.115g/cm3 and a flash point of 324.3ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 85175-67-3
Jingsj CID: J-1957036-6
Molecular Formula: C₂₆H₃₆N₂O₅
Molecular Weight: 456.57400 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	612.5ºC at 760 mmHg
Density	1.115g/cm3
Flash Point	324.3ºC
Exact Mass	456.26200
PSA	60.47000
LogP	3.15070
Refractive Index	1.545
Storage Conditions	2-8℃

Activity & Biological Data

Additional Information	[1]. Gill CH, et al. Characterization of the human HCN1 channel and its inhibition by capsazepine. Br J Pharmacol. 2004 Oct;143(3):411-21. [2]. Van Bogaert PP, et al. Use-dependent blockade of cardiac pacemaker current (If) by cilobradine and zatebradine. Eur J Pharmacol. 2003 Oct 8;478(2-3):161-71. [3]. Matt L, et al. HCN2 channels in local inhibitory interneurons constrain LTP in the hippocampal direct perforant path. Cell Mol Life Sci. 2011 Jan;68(1):125-37.

Additional Information

[1]. Gill CH, et al. Characterization of the human HCN1 channel and its inhibition by capsazepine. Br J Pharmacol. 2004 Oct;143(3):411-21. [2]. Van Bogaert PP, et al. Use-dependent blockade of cardiac pacemaker current (If) by cilobradine and zatebradine. Eur J Pharmacol. 2003 Oct 8;478(2-3):161-71. [3]. Matt L, et al. HCN2 channels in local inhibitory interneurons constrain LTP in the hippocampal direct perforant path. Cell Mol Life Sci. 2011 Jan;68(1):125-37.

Frequently Asked Questions

What is the CAS number of Zatebradine?

The CAS number of Zatebradine is 85175-67-3.

What are the molecular formula and molecular weight of Zatebradine?

Zatebradine has molecular formula C26H36N2O5 and molecular weight 456.57400 g/mol.

What are the upstream and downstream products of Zatebradine?

For Zatebradine, Upstream Products: Formaldehyde, N-Methyl-N-(3-chloropropyl)-3,4-dimethoxyphenethylamine, 7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Zatebradine (CAS 85175-67-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1957036-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.