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tert-Butyl 3-(hydroxymethyl)azetidine-1-carboxylate

Also known as: 1-Boc-azetidine-3-yl-methanol, 1-Boc-3-azetidinemethanol, 1-Boc-3-(hydroxymethyl)azetidine, Boc-Azetidin-3-ylMethanol, TERT-BUTYL 3-(HYDROXYMETHYL)AZETIDINE-1-CARBOXYLATE, 3-HYDROXYMETHYL-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER, 1-(tert-Butoxycarbonyl)-3-azetidinemethanol, 1-Azetidinecarboxylic acid, 3-(hydroxymethyl)-, 1,1-dimethylethyl ester, EOS-61767

tert-Butyl 3-(hydroxymethyl)azetidine-1-carboxylate (CAS 142253-56-3) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C9H17NO3 and a molecular weight of 187.236 g/mol. Key properties include a melting point of 55 °C, a boiling point of 270.3±13.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 117.3±19.8 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
142253-56-3
Jingsj CID
J-1956900-7
Molecular Formula
C9H17NO3
Molecular Weight
187.236 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point55 °C
Boiling Point270.3±13.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point117.3±19.8 °C
Exact Mass187.120850
PSA49.77000
LogP0.01
Vapor Pressure0.0±1.2 mmHg at 25°C
Refractive Index1.489
Additional PropertySoluble in Dimethyl sulfoxide (DMSO).

Activity & Biological Data

TargetNon-cleavable
Additional Information[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Customs & Trade Information

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of tert-Butyl 3-(hydroxymethyl)azetidine-1-carboxylate?

The CAS number of tert-Butyl 3-(hydroxymethyl)azetidine-1-carboxylate is 142253-56-3.

What are the molecular formula and molecular weight of tert-Butyl 3-(hydroxymethyl)azetidine-1-carboxylate?

tert-Butyl 3-(hydroxymethyl)azetidine-1-carboxylate has molecular formula C9H17NO3 and molecular weight 187.236 g/mol.

What are the upstream and downstream products of tert-Butyl 3-(hydroxymethyl)azetidine-1-carboxylate?

For tert-Butyl 3-(hydroxymethyl)azetidine-1-carboxylate, Upstream Products: 1-(tert-Butoxycarbonyl)azetidine-3-carboxylic acid, Methyl 1-Boc-azetidine-3-carboxylate, (1-Benzhydrylazetidin-3-yl)methanol; Downstream Products: tert-butyl 3-[(methanesulfonyloxy)methyl]azetidine-1-carboxylate, Azetidin-3-ylmethanol, tert-Butyl 3-(iodomethyl)azetidine-1-carboxylate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "tert-Butyl 3-(hydroxymethyl)azetidine-1-carboxylate (CAS 142253-56-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1956900-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.