12,14-Dichlorodehydroabietic acid

Also known as: 12,14-Dichlorodehydroabietic acid, Dichlorodehydroabietic acid, Dichloroabietic acid, 12,14-Dichloroabieta-8(14),9(11),12-triene-18-oic acid, 12,14-Dichloroabieta-8,11,13-trien-18-oic acid, (1R,4aS,10aR)-6,8-dichloro-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid, (1R)-1,4aβ-dimethyl-6,8-dichloro-7-isopropyl-1,2,3,4,4a,9,10,10aα-octahydrophenanthrene-1α-carboxylic acid, 1-Phenanthrenecarboxylic acid, 6,8-dichloro-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aS,10aR)-

12,14-Dichlorodehydroabietic acid (CAS 65281-77-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C20H26Cl2O2 and a molecular weight of 369.32500 g/mol. Key properties include a boiling point of 469.6ºC at 760 mmHg, a density of 1.2g/cm3 and a flash point of 237.8ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 65281-77-8
Jingsj CID: J-1956655-3
Molecular Formula: C₂₀H₂₆Cl₂O₂
Molecular Weight: 369.32500 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	469.6ºC at 760 mmHg
Density	1.2g/cm3
Flash Point	237.8ºC
Exact Mass	368.13100
PSA	37.30000
LogP	6.21170
Refractive Index	1.555

Activity & Biological Data

Target	Ca2+-activated K+ (BK) channel[2] GABAA[1]
Additional Information	[1]. R A Nicholson, et al. Inhibition of GABA-gated chloride channels by 12,14-dichlorodehydroabietic acid in mammalian brain. Br J Pharmacol. 1999 Mar;126(5):1123-32. [2]. Kazuho Sakamoto, et al. Molecular mechanisms for large conductance Ca2+-activated K+ channel activation by a novel opener, 12,14-dichlorodehydroabietic acid. J Pharmacol Exp Ther. 2006 Jan;316(1):144-53.

Frequently Asked Questions

What is the CAS number of 12,14-Dichlorodehydroabietic acid?

The CAS number of 12,14-Dichlorodehydroabietic acid is 65281-77-8.

What are the molecular formula and molecular weight of 12,14-Dichlorodehydroabietic acid?

12,14-Dichlorodehydroabietic acid has molecular formula C20H26Cl2O2 and molecular weight 369.32500 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "12,14-Dichlorodehydroabietic acid (CAS 65281-77-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1956655-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.