6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile
Also known as: 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile, 6-(5-bromo-2-hydroxyphenyl)-1,2-dihydro-2-oxo-4-phenyl-3-pyridinecarbonitrile, 3-Pyridinecarbonitrile, 6-(5-bromo-2-hydroxyphenyl)-1,2-dihydro-2-oxo-4-phenyl-, TCS PIM-1 1, SC 204330, CS-1482, 6-(5-Bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile
6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile (CAS 491871-58-0) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C18H11BrN2O2 and a molecular weight of 367.196 g/mol. Key properties include a boiling point of 592.6±50.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 312.2±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 491871-58-0
- Jingsj CID
- J-1956576-5
- Molecular Formula
- C18H11BrN2O2
- Molecular Weight
- 367.196 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 592.6±50.0 °C at 760 mmHg |
|---|---|
| Density | 1.6±0.1 g/cm3 |
| Flash Point | 312.2±30.1 °C |
| Exact Mass | 366.000397 |
| PSA | 77.14000 |
| LogP | 4.60 |
| Vapor Pressure | 0.0±1.7 mmHg at 25°C |
| Refractive Index | 1.728 |
| Storage Conditions | 2-8℃ |
Activity & Biological Data
| Additional Information | [1]. Cheney IW, et al. Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1679-83. [2]. Shen Y, et al. Pim-1 inhibitor attenuates trinitrobenzene sulphonic acid induced colitis in the mice. Clin Res Hepatol Gastroenterol. 2018 Sep;42(4):382-386. |
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Frequently Asked Questions
What is the CAS number of 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile?
The CAS number of 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile is 491871-58-0.
What are the molecular formula and molecular weight of 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile?
6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile has molecular formula C18H11BrN2O2 and molecular weight 367.196 g/mol.
What are the upstream and downstream products of 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile?
For 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile, Upstream Products: 1-(5-Bromo-2-hydroxyphenyl)-3-phenyl-1,3-propanedione, 2-Cyanoacetamide.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile (CAS 491871-58-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1956576-5 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.