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Tipepidine

Also known as: Asverin, AT 327, CR 662, Bitiodin, Tipedine, 3-(Di-2-thienylmethylene)-1-methylpiperidine, 1-Methyl-3-piperidylidenedi(2-thienyl)methane, 3-(Dithien-2-ylmethylene)-1-methylpiperidine

Tipepidine (CAS 5169-78-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C15H17NS2 and a molecular weight of 275.44200 g/mol. Key properties include a melting point of 64-65°, a boiling point of bp4-5 178-184° and a density of 1.1947 (rough estimate). No supplier offers are currently listed; request a quote. Record last updated Nov 4, 2026.

CAS No.
5169-78-8
Jingsj CID
J-1956250-6
Molecular Formula
C15H17NS2
Molecular Weight
275.44200 g/mol
Category
Organic Compounds
Last updated
11/4/2026

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Physicochemical Properties

Melting Point64-65°
Boiling Pointbp4-5 178-184°
Density1.1947 (rough estimate)
Exact Mass275.08000
PSA59.72000
LogP4.27500
Refractive Index1.5300 (estimate)

Activity & Biological Data

TargetIC50: 7.0 μM (dopamine D2 receptor)[1]
Additional Information[1]. Hamasaki R, et al. Tipepidine activates VTA dopamine neuron via inhibiting dopamine D₂ receptor-mediated inward rectifying K⁺ current. Neuroscience. 2013 Nov 12;252:24-34. [2]. Kawaura K, et al. Tipepidine, a non-narcotic antitussive, exerts an antidepressant-like effect in the forced swimming test in adrenocorticotropic hormone-treated rats. Behav Brain Res. 2016 Apr 1;302:269-78.

Customs & Trade Information

HS Code2934999090
Summary2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Tipepidine?

The CAS number of Tipepidine is 5169-78-8.

What are the molecular formula and molecular weight of Tipepidine?

Tipepidine has molecular formula C15H17NS2 and molecular weight 275.44200 g/mol.

What are the upstream and downstream products of Tipepidine?

For Tipepidine, Upstream Products: 2-Bromothiophene, Methyl 1-methylpiperidine-3-carboxylate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Tipepidine (CAS 5169-78-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1956250-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.