5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

Also known as: RU 24969, RU24969, CS-1199, 3-(1,2,3,6-Tetrahydropyridine-4-yl)-5-methoxy-1H-indole, 1H-Indole, 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-

5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (CAS 66611-26-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C14H16N2O and a molecular weight of 228.29000 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 66611-26-5
Jingsj CID: J-1956205-1
Molecular Formula: C₁₄H₁₆N₂O
Molecular Weight: 228.29000 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Exact Mass	228.12600
PSA	37.05000
LogP	2.88200
Storage Conditions	2-8℃

Activity & Biological Data

Additional Information	[1]. Doods HN, et al. Differential selectivities of RU 24969 and 8-OH-DPAT for the purported 5-HT1A and 5-HT1B binding sites. Correlation between 5-HT1A affinity and hypotensive activity. Eur J Pharmacol. 1985 Jun 19;112(3):363-70. [2]. Green AR, et al. The behavioural effects of RU 24969, a suggested 5-HT1 receptor agonist in rodents and the effect on the behaviour of treatment with antidepressants. Neuropharmacology. 1984 Jun;23(6):655-61. [3]. Aronsen D, et al. RU 24969-produced adipsia and hyperlocomotion: Differential role of 5HT1A and 5HT1B receptor mechanisms. Pharmacol Biochem Behav. 2014 May 15;124C:1-4. [4]. Cheetham SC, et al. Evidence that RU 24969-induced locomotor activity in C57/B1/6 mice is specifically mediated by the 5-HT1B receptor. Br J Pharmacol. 1993 Dec;110(4):1621-9.

Additional Information

[1]. Doods HN, et al. Differential selectivities of RU 24969 and 8-OH-DPAT for the purported 5-HT1A and 5-HT1B binding sites. Correlation between 5-HT1A affinity and hypotensive activity. Eur J Pharmacol. 1985 Jun 19;112(3):363-70. [2]. Green AR, et al. The behavioural effects of RU 24969, a suggested 5-HT1 receptor agonist in rodents and the effect on the behaviour of treatment with antidepressants. Neuropharmacology. 1984 Jun;23(6):655-61. [3]. Aronsen D, et al. RU 24969-produced adipsia and hyperlocomotion: Differential role of 5HT1A and 5HT1B receptor mechanisms. Pharmacol Biochem Behav. 2014 May 15;124C:1-4. [4]. Cheetham SC, et al. Evidence that RU 24969-induced locomotor activity in C57/B1/6 mice is specifically mediated by the 5-HT1B receptor. Br J Pharmacol. 1993 Dec;110(4):1621-9.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole?

The CAS number of 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole is 66611-26-5.

What are the molecular formula and molecular weight of 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole?

5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole has molecular formula C14H16N2O and molecular weight 228.29000 g/mol.

What are the upstream and downstream products of 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole?

For 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole, Upstream Products: 5-Methoxyindole; Downstream Products: 5-Methoxy-3-piperidin-4-yl-1H-indole.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (CAS 66611-26-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1956205-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.