Benzocaine

Also known as: Ethyl 4-aminobenzoate, 4-Aminobenzoic acid ethyl ester, 4-ethoxycarbonylaniline, Ethyl p-aminobenzoate, Anesthesin, Parathesin, Americaine, Anaesthesin, Anaesthin, Anbesol, Benzocainum, Ethoform, Euphagin, Norcain, Norcaine, Ora-jel, Solu H, Topcaine, p-aminobenzoic acid ethyl ester, ethyl 4-aminobenzoate

Benzocaine (CAS 94-09-7) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C9H11NO2 and a molecular weight of 165.189 g/mol. Key properties include a melting point of 88-90 °C, a boiling point of 310.7±15.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 164.2±17.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 94-09-7
Jingsj CID: J-1956201-7
Molecular Formula: C₉H₁₁NO₂
Molecular Weight: 165.189 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	88-90 °C
Boiling Point	310.7±15.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	164.2±17.9 °C
Exact Mass	165.078979
PSA	52.32000
LogP	1.95
Vapor Pressure	0.0±0.7 mmHg at 25°C
Refractive Index	1.555

Activity & Biological Data

Target	IC50: 0.8 mM (Na+ channel)[1].
Additional Information	[1]. Wang GK et al. A common local anesthetic receptor for benzocaine and etidocaine in voltage-gated mu1 Na+ channels. Pflugers Arch. 1998 Jan;435(2):293-302. [2]. Di Croce D et al. Drug action of benzocaine on the sarcoplasmic reticulum Ca-ATPase from fast-twitch skeletal muscle. Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388(11):1163-70. [3]. Davis JA, et al. Benzocaine-induced methemoglobinemia attributed to topical application of the anesthetic in several laboratory animal species. Am J Vet Res. 1993 Aug;54(8):1322-6.

Target

IC50: 0.8 mM (Na+ channel)[1].

Additional Information

[1]. Wang GK et al. A common local anesthetic receptor for benzocaine and etidocaine in voltage-gated mu1 Na+ channels. Pflugers Arch. 1998 Jan;435(2):293-302. [2]. Di Croce D et al. Drug action of benzocaine on the sarcoplasmic reticulum Ca-ATPase from fast-twitch skeletal muscle. Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388(11):1163-70. [3]. Davis JA, et al. Benzocaine-induced methemoglobinemia attributed to topical application of the anesthetic in several laboratory animal species. Am J Vet Res. 1993 Aug;54(8):1322-6.

Customs & Trade Information

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Benzocaine?

The CAS number of Benzocaine is 94-09-7.

What are the molecular formula and molecular weight of Benzocaine?

Benzocaine has molecular formula C9H11NO2 and molecular weight 165.189 g/mol.

What are the upstream and downstream products of Benzocaine?

For Benzocaine, Upstream Products: Ethyl 4-iodobenzoate, Ethanol, 4-aminobenzoic acid; Downstream Products: 4-Hydroxy-2-methylquinoline-6-carboxylic acid, ethyl 4-(tert-butoxycarbonylamino)benzoate, ethyl 4-(phenylthio)benzoate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Benzocaine (CAS 94-09-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1956201-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.