![Molecular structure of 7-methyl-2-(morpholin-4-yl)-9-[1-(phenylamino)ethyl]pyrido[1,2-a]pyrimidin-4-one (CAS 663619-89-4)](/images/chem_structures_svg/406/663619-89-4.svg)
7-methyl-2-(morpholin-4-yl)-9-[1-(phenylamino)ethyl]pyrido[1,2-a]pyrimidin-4-one
Also known as: TGX-221, TGX221, (+/-)-7-methyl-2-morpholin-4-yl-9-(1-phenylaminoethyl)pyrido[1,2-a]pyrimidin-4-one, 4H-Pyrido[1,2-a]pyrimidin-4-one, 7-methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-, 7-methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one, 7-methyl-2-morpholino-9-(1-(phenylamino)ethyl)-4H-pyrido[1,2-a]pyrimidin-4-one, 9-(1-Anilinoethyl)-7-methyl-2-(4-morpholinyl)-4H-pyrido[1,2-a]pyrimidin-4-one, 9-(1-Anilinoethyl)-7-methyl-2-(morpholin-4-yl)-4H-pyrido[1,2-a]pyrimidin-4-one, 9-(1-anilinoethyl)-7-methyl-2-morpholin-4-ylpyrido[1,2-a]pyrimidin-4-one, UNII:6L28AW98TH
7-methyl-2-(morpholin-4-yl)-9-[1-(phenylamino)ethyl]pyrido[1,2-a]pyrimidin-4-one (CAS 663619-89-4) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C21H24N4O2 and a molecular weight of 364.441 g/mol. Key properties include a boiling point of 557.3±60.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 290.8±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 663619-89-4
- Jingsj CID
- J-1955970-7
- Molecular Formula
- C21H24N4O2
- Molecular Weight
- 364.441 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 557.3±60.0 °C at 760 mmHg |
|---|---|
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 290.8±32.9 °C |
| Exact Mass | 364.189911 |
| PSA | 58.87000 |
| LogP | 3.19 |
| Vapor Pressure | 0.0±1.5 mmHg at 25°C |
| Refractive Index | 1.646 |
| Storage Conditions | -20℃ |
Activity & Biological Data
| Target | p110β:8.5 nM (IC50) p110δ:211 nM (IC50) |
|---|---|
| Additional Information | [1]. Zhao Y, et al. Prodrug strategy for PSMA-targeted delivery of TGX-221 to prostate cancer cells. Mol Pharm. 2012 Jun 4;9(6):1705-16. [2]. Ge Q, et al. The phosphoinositide 3'-kinase p110δ modulates contractile protein production and IL-6 release in human airway smooth muscle. J Cell Physiol. 2012 Aug;227(8):3044-52. [3]. Müller KM, et al. Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells. BMC Cancer. 2011 Oct 2;11:421. [4]. Sturgeon SA, et al. Advantages of a selective beta-isoform phosphoinositide 3-kinase antagonist, an anti-thrombotic agent devoid of other cardiovascular actions in the rat. Eur J Pharmacol. 2008 Jun 10;587(1-3):209-15. [5]. Chaussade C, et al. Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling. Biochem J. 2007 Jun 15;404(3):449-58. |
Frequently Asked Questions
What is the CAS number of 7-methyl-2-(morpholin-4-yl)-9-[1-(phenylamino)ethyl]pyrido[1,2-a]pyrimidin-4-one?
The CAS number of 7-methyl-2-(morpholin-4-yl)-9-[1-(phenylamino)ethyl]pyrido[1,2-a]pyrimidin-4-one is 663619-89-4.
What are the molecular formula and molecular weight of 7-methyl-2-(morpholin-4-yl)-9-[1-(phenylamino)ethyl]pyrido[1,2-a]pyrimidin-4-one?
7-methyl-2-(morpholin-4-yl)-9-[1-(phenylamino)ethyl]pyrido[1,2-a]pyrimidin-4-one has molecular formula C21H24N4O2 and molecular weight 364.441 g/mol.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "7-methyl-2-(morpholin-4-yl)-9-[1-(phenylamino)ethyl]pyrido[1,2-a]pyrimidin-4-one (CAS 663619-89-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955970-7 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.