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Clomethiazole

Also known as: 5-(2-chloroethyl)-4-methylthiazole, Chlormethiazole, Chlorethiazole, Chlormethiazol, Clomethiazol, Clomethiazolum, Clometiazole, Distraneurin, Emineurina

Clomethiazole (CAS 533-45-9) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C6H8ClNS and a molecular weight of 161.65500 g/mol. Key properties include a boiling point of 245.8ºC at 760 mmHg, a density of 1.218 g/cm3 and a flash point of 102.4ºC. No supplier offers are currently listed; request a quote. Record last updated Nov 2, 2026.

CAS No.
533-45-9
Jingsj CID
J-1955875-9
Molecular Formula
C6H8ClNS
Molecular Weight
161.65500 g/mol
Category
Pharma Intermediates
Last updated
11/2/2026

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Physicochemical Properties

Boiling Point245.8ºC at 760 mmHg
Density1.218 g/cm3
Flash Point102.4ºC
Exact Mass196.98300
PSA41.13000
LogP3.03480

Activity & Biological Data

Additional Information[1]. Nelson RM, et al.Electrophysiological actions of gamma-aminobutyric acid and clomethiazole on recombinant GABA(A) receptors.Eur J Pharmacol. 2002 Oct 11;452(3):255-62. [2]. Stresser DM, et al. Selective Time- and NADPH-Dependent Inhibition of Human CYP2E1 by Clomethiazole.Drug Metab Dispos. 2016 Aug;44(8):1424-30

Customs & Trade Information

HS Code2934100090
Summary2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Clomethiazole?

The CAS number of Clomethiazole is 533-45-9.

What are the molecular formula and molecular weight of Clomethiazole?

Clomethiazole has molecular formula C6H8ClNS and molecular weight 161.65500 g/mol.

What are the upstream and downstream products of Clomethiazole?

For Clomethiazole, Upstream Products: 2-(4-Methyl-1,3-thiazol-5-yl)ethanol, 5-(2-ethoxyethyl)-4-methylthiazole, 3-chloro-5-hydroxy-2-pentanone; Downstream Products: 4-Methyl-5-vinylthiazole, 2-(4-Methylthiazol-5-yl)ethanamine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Clomethiazole (CAS 533-45-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955875-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.