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Haloperidol

Also known as: 4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butan-1-one, Haldol, Serenace, Aloperidin, Brotopon, Einalon, Halosten, Keselan, Peluces, Pernox, Sernas, Sernel, Sigaperidol, r1625

Haloperidol (CAS 52-86-8) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C21H23ClFNO2 and a molecular weight of 375.864 g/mol. Key properties include a melting point of 152 °C, a boiling point of 529.0±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 273.8±30.1 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H315 — Causes skin irritation and H317 — May cause an allergic skin reaction. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
52-86-8
Jingsj CID
J-19558-8
Molecular Formula
C21H23ClFNO2
Molecular Weight
375.864 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point152 °C
Boiling Point529.0±50.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point273.8±30.1 °C
Exact Mass375.140137
PSA40.54000
LogP3.01
Vapor Pressure0.0±1.5 mmHg at 25°C
Refractive Index1.581
Additional Property45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.39 mg/mL

GHS Safety & Compliance

Acute Toxicity / Health HazardSignal word: Danger
  • H301 — Toxic if swallowed
  • H315 — Causes skin irritation
  • H317 — May cause an allergic skin reaction
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation
  • H361 — Suspected of damaging fertility or the unborn child

Activity & Biological Data

Additional Information[1]. Furuta Y, et al. Effects of enzyme inhibitors of catecholamine metabolism and of haloperidol on the pancreatic secretion induced by L-DOPA and by dopamine in dogs. Br J Pharmacol. 1973 Jan;47(1):77-84. [2]. Shah NS, et al. Effects of chlorpromazine and haloperidol on the disposition of mescaline-14C in mice. J Pharmacol Exp Ther. 1973 Aug;186(2):297-304.

Customs & Trade Information

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Haloperidol?

The CAS number of Haloperidol is 52-86-8.

What are the molecular formula and molecular weight of Haloperidol?

Haloperidol has molecular formula C21H23ClFNO2 and molecular weight 375.864 g/mol.

Is Haloperidol hazardous?

Haloperidol has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H315 — Causes skin irritation; H317 — May cause an allergic skin reaction.

What are the upstream and downstream products of Haloperidol?

For Haloperidol, Upstream Products: 4-(4-Chlorophenyl)piperidin-4-ol, 4-Chloro-4'-fluorobutyrophenone, Methyl 4-(4-fluorophenyl)-4-oxobutanoate; Downstream Products: 4-Fluorobenzaldehyde, 4'-Fluoroacetophenone, Chlorobenzene.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Haloperidol (CAS 52-86-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-19558-8 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.