Polydatin

Also known as: Piceid, Resveratrol 3-β-D-glucopyranoside, Resveratrol 3-glucoside, Resveratrol 3-O-β-D-glucopyranoside, trans-Polydatin, 3-Hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenyl β-D-glucopyranoside, 4',5-Dihydroxystilben-3-yl β-D-glucopyranoside, Pieceid, Plydatin, Polydotin peceid, MFCD00210592, β-D-Glucopyranoside, 3-hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl

Polydatin (CAS 27208-80-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H22O8 and a molecular weight of 390.384 g/mol. Key properties include a melting point of 223-226ºC (dec.), a boiling point of 707.7±60.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 381.8±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 27208-80-6
Jingsj CID: J-1955756-3
Molecular Formula: C₂₀H₂₂O₈
Molecular Weight: 390.384 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	223-226ºC (dec.)
Boiling Point	707.7±60.0 °C at 760 mmHg
Density	1.5±0.1 g/cm3
Flash Point	381.8±32.9 °C
Exact Mass	390.131470
PSA	139.84000
LogP	1.00
Vapor Pressure	0.0±2.4 mmHg at 25°C
Refractive Index	1.737

Activity & Biological Data

Target	NF-κB, Autophagy
Additional Information	[1]. Cheng Y, et al. Involvement of cell adhesion molecules in polydatin protection of brain tissues from ischemia-reperfusioninjury. Brain Res. 2006 Sep 19;1110(1):193-200. [2]. Wang HL, et al. Synergistic effects of Polydatin and Vitamin C in Inhibiting Cardiotoxicity induced by Doxorubicin in rats. Fundam Clin Pharmacol. 2016 Nov 28. [Epub ahead of print] [3]. Jiang KF, et al. Polydatin ameliorates Staphylococcus aureus-induced mastitis in mice via inhibiting TLR2-mediated activation of the p38 MAPK/NF-κB pathway. Acta Pharmacol Sin. 2016 Nov 28. [Epub ahead of print]

Target

NF-κB, Autophagy

Additional Information

[1]. Cheng Y, et al. Involvement of cell adhesion molecules in polydatin protection of brain tissues from ischemia-reperfusioninjury. Brain Res. 2006 Sep 19;1110(1):193-200. [2]. Wang HL, et al. Synergistic effects of Polydatin and Vitamin C in Inhibiting Cardiotoxicity induced by Doxorubicin in rats. Fundam Clin Pharmacol. 2016 Nov 28. [Epub ahead of print] [3]. Jiang KF, et al. Polydatin ameliorates Staphylococcus aureus-induced mastitis in mice via inhibiting TLR2-mediated activation of the p38 MAPK/NF-κB pathway. Acta Pharmacol Sin. 2016 Nov 28. [Epub ahead of print]

Frequently Asked Questions

What is the CAS number of Polydatin?

The CAS number of Polydatin is 27208-80-6.

What are the molecular formula and molecular weight of Polydatin?

Polydatin has molecular formula C20H22O8 and molecular weight 390.384 g/mol.

What are the upstream and downstream products of Polydatin?

For Polydatin, Upstream Products: trans-Desoxyrhaponticin, Resveratrol, 2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl bromide; Downstream Products: Resveratrol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Polydatin (CAS 27208-80-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955756-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.