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WZ4002

Also known as: 2-Propenamide, N-[3-[[5-chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]-, CS-166, N-(3-(5-chloro-2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yloxy)phenyl)acrylamide, N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide, N-[3-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]-2-propenamide, N-[3-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]-2-propenamide WZ 4002, N-{3-[(5-Chloro-2-{[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino}-4-pyriMidinyl)oxy]phenyl}acrylaMide, N-{3-[(5-Chloro-2-{[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)oxy]phenyl}acrylamide, N-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide, S1173_Selleck, WZ 4002 N-[3-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]-2-propenamide, WZ-4002, WZ-4002,WZ4002, WZ4002(HBr)

WZ4002 (CAS 1213269-23-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C25H27ClN6O3 and a molecular weight of 494.973 g/mol. Key property: a density of 1.3±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
1213269-23-8
Jingsj CID
J-1955566-9
Molecular Formula
C25H27ClN6O3
Molecular Weight
494.973 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Density1.3±0.1 g/cm3
Exact Mass494.183319
PSA95.34000
LogP3.48
Refractive Index1.648

Activity & Biological Data

TargetEGFRL858R:2 nM (IC50, Cell Assay) EGFRL858R/T790M:8 nM (IC50, Cell Assay) EGFRE746_A750:3 nM (IC50, Cell Assay) EGFRE746_A750/T790M:2 nM (IC50, Cell Assay)
Additional Information[1]. Zhou W, et al. Novel mutant-selective EGFR kinase inhibitors against EGFR T790M.Nature. 2009 Dec 24;462(7276):1070-4.

Frequently Asked Questions

What is the CAS number of WZ4002?

The CAS number of WZ4002 is 1213269-23-8.

What are the molecular formula and molecular weight of WZ4002?

WZ4002 has molecular formula C25H27ClN6O3 and molecular weight 494.973 g/mol.

What are the upstream and downstream products of WZ4002?

For WZ4002, Upstream Products: Acryloyl chloride, 2-Methoxy-4-(4-methylpiperazin-1-yl)aniline, 3-Nitrophenol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "WZ4002 (CAS 1213269-23-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955566-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.