Lixivaptan
Also known as: VPA-985, WAY-VPA-985, N-[3-chloro-4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)phenyl]-5-fluoro-2-methylbenzamide, N-[3-chloro-4-(6,11-dihydropyrrolo[2,1-c][1,4]benzodiazepine-5-carbonyl)phenyl]-5-fluoro-2-methylbenzamide
Lixivaptan (CAS 168079-32-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C27H21ClFN3O2 and a molecular weight of 473.926 g/mol. Key properties include a boiling point of 626.5±55.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 332.7±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 168079-32-1
- Jingsj CID
- J-1955480-4
- Molecular Formula
- C27H21ClFN3O2
- Molecular Weight
- 473.926 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 626.5±55.0 °C at 760 mmHg |
|---|---|
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 332.7±31.5 °C |
| Exact Mass | 473.130646 |
| PSA | 57.83000 |
| LogP | 7.23 |
| Vapor Pressure | 0.0±1.8 mmHg at 25°C |
| Refractive Index | 1.658 |
Activity & Biological Data
| Target | IC50: 1.2 nM (human V2), 2.3 nM (rat V2)[1] |
|---|---|
| Additional Information | [1]. Albright JD, et al. 5-Fluoro-2-methyl-N-[4-(5H-pyrrolo[2,1-c]-[1, 4]benzodiazepin-10(11H)-ylcarbonyl)-3-chlorophenyl]benzamide (VPA-985): an orally active arginine vasopressin antagonist with selectivity for V2 receptors. J Med Chem. 1998 Jul 2;41(14):2442-4. [2]. Ghali JK, et al. Lixivaptan, a non-peptide vasopressin V2 receptor antagonist for the potential oral treatment of hyponatremia. IDrugs. 2010 Nov;13(11):782-92. |
Frequently Asked Questions
What is the CAS number of Lixivaptan?
The CAS number of Lixivaptan is 168079-32-1.
What are the molecular formula and molecular weight of Lixivaptan?
Lixivaptan has molecular formula C27H21ClFN3O2 and molecular weight 473.926 g/mol.
What are the upstream and downstream products of Lixivaptan?
For Lixivaptan, Upstream Products: 10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine, Methyl 4-amino-2-chlorobenzoate, 5-Fluoro-2-methylbenzoyl chloride.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Lixivaptan (CAS 168079-32-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955480-4 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.