rac 5-Hydroxymethyl Tolterodine

Also known as: rac 5-Hydroxymethyl Tolterodine, 2-(3-(Diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol, 5-Hydroxymethyl rac-Tolterodine, Benzenemethanol, 3-[3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxy-, Fesoterodine Impurity A, N,N-diisopropyl-3-(2-hydroxy-5-hydroxymethylphenyl)-3-phenylpropylamine, RS-N,N-diisopropyl-3-(2-hydroxy-5-(hydroxymethyl)phenyl)-3-phenylpropylamine, rac 5-Hydroxymethyl Tolterodine, 90% by HPLC

rac 5-Hydroxymethyl Tolterodine (CAS 200801-70-3) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C22H31NO2 and a molecular weight of 341.49 g/mol. Key properties include a boiling point of 490.7±45.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 233.2±27.4 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 200801-70-3
Jingsj CID: J-1955471-3
Molecular Formula: C₂₂H₃₁NO₂
Molecular Weight: 341.49 g/mol
Category: Alcohols
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	490.7±45.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	233.2±27.4 °C
Exact Mass	341.235474
PSA	43.70000
LogP	4.12
Vapor Pressure	0.0±1.3 mmHg at 25°C
Refractive Index	1.563

Activity & Biological Data

Target	Ki: M1 (2.3 nM), M2 (2 nM), M3 (2.5 nM), M4 (2.8 nM), and M5 (2.9 nM)[1]
Additional Information	[1]. L Nilvebrant, et al. Antimuscarinic potency and bladder selectivity of PNU-200577, a major metabolite of tolterodine. Pharmacol Toxicol. 1997 Oct;81(4):169-72. [2]. B Malhotra, et al. The design and development of fesoterodine as a prodrug of 5-hydroxymethyl tolterodine (5-HMT), the active metabolite of tolterodine. Curr Med Chem. 2009;16(33):4481-9. [3]. Shizuo Yamada, et al. Muscarinic receptor binding of fesoterodine, 5-hydroxymethyl tolterodine, and tolterodine in rat tissues after the oral, intravenous, or intravesical administration. J Pharmacol Sci. 2019 May;140(1):73-78.

Target

Ki: M1 (2.3 nM), M2 (2 nM), M3 (2.5 nM), M4 (2.8 nM), and M5 (2.9 nM)[1]

Additional Information

[1]. L Nilvebrant, et al. Antimuscarinic potency and bladder selectivity of PNU-200577, a major metabolite of tolterodine. Pharmacol Toxicol. 1997 Oct;81(4):169-72. [2]. B Malhotra, et al. The design and development of fesoterodine as a prodrug of 5-hydroxymethyl tolterodine (5-HMT), the active metabolite of tolterodine. Curr Med Chem. 2009;16(33):4481-9. [3]. Shizuo Yamada, et al. Muscarinic receptor binding of fesoterodine, 5-hydroxymethyl tolterodine, and tolterodine in rat tissues after the oral, intravenous, or intravesical administration. J Pharmacol Sci. 2019 May;140(1):73-78.

Customs & Trade Information

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of rac 5-Hydroxymethyl Tolterodine?

The CAS number of rac 5-Hydroxymethyl Tolterodine is 200801-70-3.

What are the molecular formula and molecular weight of rac 5-Hydroxymethyl Tolterodine?

rac 5-Hydroxymethyl Tolterodine has molecular formula C22H31NO2 and molecular weight 341.49 g/mol.

What are the upstream and downstream products of rac 5-Hydroxymethyl Tolterodine?

For rac 5-Hydroxymethyl Tolterodine, Upstream Products: trans-Cinnamaldehyde, 4-Hydroxybenzyl alcohol, 6-Bromo-4-phenylchroman-2-one; Downstream Products: Desfesoterodine, Fesoterodine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "rac 5-Hydroxymethyl Tolterodine (CAS 200801-70-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955471-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.