4,5-Dianilinophthalimide

Also known as: CGP 52411, CGP52411, DAPH, DAPH-1, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, 1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-, 5,6-dianilinoisoindole-1,3-dione

4,5-Dianilinophthalimide (CAS 145915-58-8) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C20H15N3O2 and a molecular weight of 329.35200 g/mol. Key properties include a melting point of 199-202℃ and a density of 1.374 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 145915-58-8
Jingsj CID: J-1955424-6
Molecular Formula: C₂₀H₁₅N₃O₂
Molecular Weight: 329.35200 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	199-202℃
Density	1.374 g/cm3
Exact Mass	329.11600
PSA	70.23000
LogP	4.53220
Storage Conditions	2-8°C

Activity & Biological Data

Target	EGFR:0.3 μM (IC50) Amyloid-β
Additional Information	[1]. Buchdunger E, et al. 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity. Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2334-8. [2]. Blanchard BJ, et al. Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule. Proc Natl Acad Sci U S A. 2004 Oct 5;101(40):14326-32.

Target

EGFR:0.3 μM (IC50) Amyloid-β

Additional Information

[1]. Buchdunger E, et al. 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity. Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2334-8. [2]. Blanchard BJ, et al. Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule. Proc Natl Acad Sci U S A. 2004 Oct 5;101(40):14326-32.

Frequently Asked Questions

What is the CAS number of 4,5-Dianilinophthalimide?

The CAS number of 4,5-Dianilinophthalimide is 145915-58-8.

What are the molecular formula and molecular weight of 4,5-Dianilinophthalimide?

4,5-Dianilinophthalimide has molecular formula C20H15N3O2 and molecular weight 329.35200 g/mol.

What are the upstream and downstream products of 4,5-Dianilinophthalimide?

For 4,5-Dianilinophthalimide, Upstream Products: 4,5-Dichlorophthalic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "4,5-Dianilinophthalimide (CAS 145915-58-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955424-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.