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Ebrotidine

Also known as: (E)-N-[[[2-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]ethyl]amino]methylene]-4-bromobenzenesulfonamide, 4-Bromo-N-[(E)-({2-[({2-[(diaminomethylene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]ethyl}imino)methyl]benzenesulfonamide, 4-bromo-N-{(E)-[(2-{[(2-carbamimidamido-1,3-thiazol-4-yl)methyl]sulfanyl}ethyl)amino]methylidene}benzenesulfonamide, Benzenesulfonamide, 4-bromo-N-[(E)-[[2-[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]ethyl]imino]methyl]-, Benzenesulfonamide,N-(((2-(((2-((aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)ethyl)amino)methylene)-4-bromo-,(E), Ebrotidina, Ebrotiding, Ebrotidinum, FI 3542, FI-3542, FI3542, N-(4-bromophenyl)sulfonyl-N'-[2-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]ethyl]methanimidamide, N-[[[2-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]ethyl]amino]methylene]-4-bromobenzenesulfonamide, ULSANIC, Ulsanic, n-p-bromobenzenesulfonyl-n'-[2-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]ethyl]formamidine, p-Bromo-N-[[[2-[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]ethyl]amino]methylene]benzenesulfonamide

Ebrotidine (CAS 100981-43-9) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C14H17BrN6O2S3 and a molecular weight of 477.423 g/mol. Key properties include a boiling point of 672.3±65.0 °C at 760 mmHg, a density of 1.7±0.1 g/cm3 and a flash point of 360.4±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
100981-43-9
Jingsj CID
J-1955267-5
Molecular Formula
C14H17BrN6O2S3
Molecular Weight
477.423 g/mol
Category
Organohalogen Compounds
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point672.3±65.0 °C at 760 mmHg
Density1.7±0.1 g/cm3
Flash Point360.4±34.3 °C
Exact Mass475.975830
PSA195.24000
LogP3.37
Vapor Pressure0.0±2.1 mmHg at 25°C
Refractive Index1.740
Storage Conditions2-8℃

Activity & Biological Data

Additional Information[1]. Agut J, Sánchez JC, Sacristán A, Action of ebrotidine, ranitidine and cimetidine on the specific binding to histamine H1- and H2-receptors. Arzneimittelforschung. 1997 Apr;47(4A):447-9. [2]. Palop D, Agut J, Márquez M, Histamine H2-receptor antagonist action of ebrotidine. Effects on gastric acid secretion, gastrin levels and NSAID-induced gastrotoxicity in the rat. Arzneimittelforschung. 1997 Apr;47(4A):439-46. [3]. Konturek SJ, Kwiecien N, Sito E, Effects of ebrotidine on aspirin-induced gastric mucosal damage and blood flow in humans. Scand J Gastroenterol. 1993 Dec;28(12):1047-50. [4]. Piotrowski J, Yamaki K, Morita M, Ebrotidine--a new H2-receptor antagonist with mucosal strengthening activity. Biochem Int. 1992 Mar;26(4):659-67.

Customs & Trade Information

HS Code2942000000

Frequently Asked Questions

What is the CAS number of Ebrotidine?

The CAS number of Ebrotidine is 100981-43-9.

What are the molecular formula and molecular weight of Ebrotidine?

Ebrotidine has molecular formula C14H17BrN6O2S3 and molecular weight 477.423 g/mol.

What are the upstream and downstream products of Ebrotidine?

For Ebrotidine, Upstream Products: 4-Bromobenzenesulfonamide, 2-[4-(Chloromethyl)-1,3-thiazol-2-yl]guanidine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Ebrotidine (CAS 100981-43-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955267-5 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.