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Tipranavir

Also known as: Tipranavir, Aptivus, PNU-140690, N-[3-[(1R)-1-[(6R)-5,6-Dihydro-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-2H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)-2-pyridinesulfonamide, N-[3-[(1R)-1-[(2R)-4-hydroxy-6-oxo-2-(2-phenylethyl)-2-propyl-3H-pyran-5-yl]propyl]phenyl]-5-(trifluoromethyl)pyridine-2-sulfonamide, TPV, UNII-ZZT404XD09, 1d4y, 2o4l

Tipranavir (CAS 174484-41-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C31H33F3N2O5S and a molecular weight of 602.66400 g/mol. Key properties include a melting point of 86-89ºC, a boiling point of 680ºC at 760mmHg, a density of 1.313g/cm3 and a flash point of 365.1ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
174484-41-4
Jingsj CID
J-1955215-9
Molecular Formula
C31H33F3N2O5S
Molecular Weight
602.66400 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point86-89ºC
Boiling Point680ºC at 760mmHg
Density1.313g/cm3
Flash Point365.1ºC
Exact Mass602.20600
PSA113.97000
LogP8.47930
Vapor Pressure0mmHg at 25°C
Refractive Index1.579
Storage Conditions2-8℃

Activity & Biological Data

TargetIC50: 66-410 nM (HIV-1 isolates)[1]
Additional Information[1]. Aoki M, et al. Loss of the protease dimerization inhibition activity of tipranavir (TPV) and its association with the acquisition of resistance to TPV by HIV-1. J Virol. 2012 Dec;86(24):13384-96. [2]. Li F, et al. Metabolism-mediated drug interactions associated with ritonavir-boosted tipranavir in mice. Drug Metab Dispos. 2010 May;38(5):871-8.

Frequently Asked Questions

What is the CAS number of Tipranavir?

The CAS number of Tipranavir is 174484-41-4.

What are the molecular formula and molecular weight of Tipranavir?

Tipranavir has molecular formula C31H33F3N2O5S and molecular weight 602.66400 g/mol.

What are the upstream and downstream products of Tipranavir?

For Tipranavir, Upstream Products: 5-(Trifluoromethyl)pyridine-2-sulfonyl chloride, 1-Phenylhexan-3-one, 3-Nitrobenzaldehyde.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Tipranavir (CAS 174484-41-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955215-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.