Sulfasalazine
Also known as: Salazosulfapyridine, Salicylazosulfapyridine, Sulphasalazine, SSZ, Azulfidine, Salazopyrin, Salicylazosulphapyridine, 5-[4-(2-Pyridylsulfamoyl)phenylazo]salicylic acid, 2-Hydroxy-5-{[4-(pyridin-2-ylsulfamoyl)phenyl]diazenyl}benzoic acid, Benzoic acid, 2-hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)-, SASP, Colo-Pleon, Gastropyrin, Salisulf, Accucol, Azopyrin, Reupirin, Rorasul, Sulcolon
Sulfasalazine (CAS 599-79-1) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C18H14N4O5S and a molecular weight of 398.393 g/mol. Key properties include a melting point of 260-265 °C (dec.)(lit.), a boiling point of 689.3±65.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 370.7±34.3 °C. It is classified under GHS with signal word Danger and hazard statements H317 — May cause an allergic skin reaction and H334 — May cause allergy or asthma symptoms if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 599-79-1
- Jingsj CID
- J-19372-2
- Molecular Formula
- C18H14N4O5S
- Molecular Weight
- 398.393 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 260-265 °C (dec.)(lit.) |
|---|---|
| Boiling Point | 689.3±65.0 °C at 760 mmHg |
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 370.7±34.3 °C |
| Exact Mass | 398.068481 |
| PSA | 149.69000 |
| LogP | 3.18 |
| Vapor Pressure | 0.0±2.3 mmHg at 25°C |
| Refractive Index | 1.691 |
| Additional Property | NH4OH 1 M: 50 mg/mL, clear, red | <0.1 g/100 mL at 25 ºC |
GHS Safety & Compliance
- H317 — May cause an allergic skin reaction
- H334 — May cause allergy or asthma symptoms if inhaled
Activity & Biological Data
| Target | RelA Autophagy |
|---|---|
| Additional Information | [1]. Wahl C, et al. Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B. J Clin Invest. 1998 Mar 1;101(5):1163-74. [2]. Sykes L, et al. Sulfasalazine augments a pro-inflammatory response in interleukin-1β-stimulated amniocytes and myocytes. Immunology. 2015 Dec;146(4):630-44. [3]. Chung WJ, et al. Sulfasalazine inhibits the growth of primary brain tumors independent of nuclear factor-kappaB. J Neurochem. 2009 Jul;110(1):182-93. |
Customs & Trade Information
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
Frequently Asked Questions
What is the CAS number of Sulfasalazine?
The CAS number of Sulfasalazine is 599-79-1.
What are the molecular formula and molecular weight of Sulfasalazine?
Sulfasalazine has molecular formula C18H14N4O5S and molecular weight 398.393 g/mol.
Is Sulfasalazine hazardous?
Sulfasalazine has GHS signal word Danger and hazard statements H317 — May cause an allergic skin reaction; H334 — May cause allergy or asthma symptoms if inhaled.
What are the upstream and downstream products of Sulfasalazine?
For Sulfasalazine, Upstream Products: Sulfapyridine, Salicylic acid; Downstream Products: 5-Aminosalicylic acid, Sulfapyridine.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Sulfasalazine (CAS 599-79-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-19372-2 (accessed 2026-11-07).
Data for reference only; verify product details with suppliers before purchase.