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2-(1-Piperazinyl)pyrimidine

Also known as: 1-(2-Pyrimidinyl)piperazine, 1-(2-Pyrimidyl)piperazine, 1-Pyrimidyl piperazine, 2-Piperazin-1-ylpyrimidine, 2-Piperazinylpyrimidine, 2-(Piperazin-1-yl)pyrimidine, 2-piperazinopyrimidine, Buspirone Impurity 1, 1-pp, PMPRZ, MFCD00040742, EINECS 244-135-5

2-(1-Piperazinyl)pyrimidine (CAS 20980-22-7) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C8H12N4 and a molecular weight of 164.208 g/mol. Key properties include a melting point of 32-34°C, a boiling point of 328.0±52.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 152.1±30.7 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
20980-22-7
Jingsj CID
J-19342-0
Molecular Formula
C8H12N4
Molecular Weight
164.208 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point32-34°C
Boiling Point328.0±52.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point152.1±30.7 °C
Exact Mass164.106201
PSA41.05000
LogP0.49
Vapor Pressure0.0±0.7 mmHg at 25°C
Refractive Index1.551

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 2-(1-Piperazinyl)pyrimidine?

The CAS number of 2-(1-Piperazinyl)pyrimidine is 20980-22-7.

What are the molecular formula and molecular weight of 2-(1-Piperazinyl)pyrimidine?

2-(1-Piperazinyl)pyrimidine has molecular formula C8H12N4 and molecular weight 164.208 g/mol.

Is 2-(1-Piperazinyl)pyrimidine hazardous?

2-(1-Piperazinyl)pyrimidine has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 2-(1-Piperazinyl)pyrimidine?

For 2-(1-Piperazinyl)pyrimidine, Upstream Products: Piperazine, 2-Chloropyrimidine, 2-(piperazin-1-yl)pyrimidine hydrochloride; Downstream Products: Buspirone hydrochloride, 2-(4-Methylpiperazin-1-yl)pyrimidine, 1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-(1-Piperazinyl)pyrimidine (CAS 20980-22-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-19342-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.