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(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine

Also known as: Morpholine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2R,3S)-, 2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine, 2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine [Aprepitant-M2], (2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine, Morpholine, 2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, [2R-[2a(R*),3a]]-

(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine (CAS 171338-27-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C20H18F7NO2 and a molecular weight of 437.35100 g/mol. Key properties include a boiling point of 387.856ºC at 760 mmHg, a density of 1.375 g/cm3 and a flash point of 188.369ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
171338-27-5
Jingsj CID
J-1926423-4
Molecular Formula
C20H18F7NO2
Molecular Weight
437.35100 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point387.856ºC at 760 mmHg
Density1.375 g/cm3
Flash Point188.369ºC
Exact Mass437.12300
PSA30.49000
LogP5.99300
Vapor Pressure0mmHg at 25°C
Refractive Index1.505

Frequently Asked Questions

What is the CAS number of (2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine?

The CAS number of (2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine is 171338-27-5.

What are the molecular formula and molecular weight of (2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine?

(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine has molecular formula C20H18F7NO2 and molecular weight 437.35100 g/mol.

What are the upstream and downstream products of (2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine?

For (2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine, Upstream Products: 4-Fluorophenylmagnesium bromide, (2R)-4-benzyl-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]morpholin-3-one, 1-[3,5-Bis(trifluoromethyl)phenyl]ethanol; Downstream Products: Aprepitant.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine (CAS 171338-27-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1926423-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.