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Milrinone

Also known as: Primacor, Corotrop, Corotrope, Milrila, 1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile, 3-Cyano-6-methyl-5-(4-pyridyl)-2-pyridone, 6-Methyl-5-(4-pyridyl)-2-pyridone-3-carbonitrile, YM-018

Milrinone (CAS 78415-72-2) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C12H9N3O and a molecular weight of 211.219 g/mol. Key properties include a melting point of >3000C, a boiling point of 448.7±45.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 225.2±28.7 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H311 — Toxic in contact with skin and H331 — Toxic if inhaled. No supplier offers are currently listed; request a quote. Record last updated Nov 3, 2026.

CAS No.
78415-72-2
Jingsj CID
J-19197-9
Molecular Formula
C12H9N3O
Molecular Weight
211.219 g/mol
Category
Organic Compounds
Last updated
11/3/2026

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Physicochemical Properties

Melting Point>3000C
Boiling Point448.7±45.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point225.2±28.7 °C
Exact Mass211.074554
PSA69.54000
LogP0.41
Vapor Pressure0.0±1.1 mmHg at 25°C
Refractive Index1.622
Additional PropertyDMSO: >10 mg/mL

GHS Safety & Compliance

Acute ToxicitySignal word: Danger
  • H301 — Toxic if swallowed
  • H311 — Toxic in contact with skin
  • H331 — Toxic if inhaled

Activity & Biological Data

Additional Information[1]. Santhosh KT, et al. Milrinone attenuates thromboxane receptor-mediated hyperresponsiveness in hypoxic pulmonary arterial myocytes. Br J Pharmacol. 2011 Jul;163(6):1223-36. [2]. Hentschel T, et al. Inhalation of the phosphodiesterase-3 inhibitor milrinone attenuates pulmonary hypertension in a rat model of congestive heart failure. Anesthesiology. 2007 Jan;106(1):124-31. [3]. Kishi T, et al. Effects of milrinone on left ventricular end-systolic pressure-volume relationship of rat hearts in situ. Clin Exp Pharmacol Physiol. 2001 Sep;28(9):737-42. [4]. Taylor MS, et al. Effect of milrinone on small mesenteric artery vasoconstriction: role of K(+) channels. Am J Physiol. 1999 Jul;277(1 Pt 1):G69-78.

Customs & Trade Information

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Milrinone?

The CAS number of Milrinone is 78415-72-2.

What are the molecular formula and molecular weight of Milrinone?

Milrinone has molecular formula C12H9N3O and molecular weight 211.219 g/mol.

Is Milrinone hazardous?

Milrinone has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H311 — Toxic in contact with skin; H331 — Toxic if inhaled.

What are the upstream and downstream products of Milrinone?

For Milrinone, Upstream Products: Carbon, 2-Cyanoacetamide, 1-(4-Pyridyl)acetone; Downstream Products: 6-Chloro-2-methyl-3,4'-bipyridine-5-carbonitrile, 2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carboxamide.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Milrinone (CAS 78415-72-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-19197-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.