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Alfacalcidol

Also known as: 1α-Hydroxycholecalciferol, 1α-Hydroxyvitamin D3, Alphacalcidol, 1-Hydroxycholecalciferol, 1-alpha-Hydroxycholecalciferol, Alfarol, Etalpha, One-α

Alfacalcidol (CAS 41294-56-8) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C27H44O2 and a molecular weight of 400.637 g/mol. Key properties include a melting point of 134-136°C, a boiling point of 531.5±50.0 °C at 760 mmHg, a density of 1.0±0.1 g/cm3 and a flash point of 222.6±24.7 °C. It is classified under GHS with signal word Danger and hazard statements H300, H310 and H330 — Fatal if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
41294-56-8
Jingsj CID
J-18947-9
Molecular Formula
C27H44O2
Molecular Weight
400.637 g/mol
Category
Alcohols
Last updated
8/21/2026

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Physicochemical Properties

Melting Point134-136°C
Boiling Point531.5±50.0 °C at 760 mmHg
Density1.0±0.1 g/cm3
Flash Point222.6±24.7 °C
Exact Mass400.334137
PSA40.46000
LogP8.31
Vapor Pressure0.0±3.2 mmHg at 25°C
Refractive Index1.534

GHS Safety & Compliance

Acute ToxicitySignal word: Danger
  • H300
  • H310
  • H330 — Fatal if inhaled

Activity & Biological Data

Additional Information[1]. Shiraishi et al (2000) Alfacalcidol inhibits bone resorption and stmulates formation in an ovariectomized rat model of osteoporosis: Distinct actions from estrogen. Journal of Bone and Mineral Research. 15 770. [2]. Ringe JD, Schacht E. et al. Prevention and therapy of osteoporosis: the roles of plain vitamin D and alfacalcidol. Rheumatol Int. 2004 Jul;24(4):189-97. [3]. Ivarsen P, Povlsen JV, Christensen KL.Effect of alfacalcidol on cardiac function in patients with chronic kidney disease stage 4 and secondary hyperparathyroidism: A pilot study.Scand J Urol Nephrol. 2012 Jun 25. [4]. Rianthavorn P,et al. Prevention of bone loss in children receiving long-term glucocorticoids with calcium and alfacalcidol or menatetrenone.J Pediatr Endocrinol Metab. 2012;25(3-4):307-12. [5]. Ringe JD, Farahmand P, Schacht E.Alfacalcidol in men with osteoporosis: a prospective, observational, 2-year trial on 214 patients.Rheumatol Int. 2012 Apr 8.

Customs & Trade Information

HS Code29361000

Frequently Asked Questions

What is the CAS number of Alfacalcidol?

The CAS number of Alfacalcidol is 41294-56-8.

What are the molecular formula and molecular weight of Alfacalcidol?

Alfacalcidol has molecular formula C27H44O2 and molecular weight 400.637 g/mol.

Is Alfacalcidol hazardous?

Alfacalcidol has GHS signal word Danger and hazard statements H300; H310; H330 — Fatal if inhaled.

What are the upstream and downstream products of Alfacalcidol?

For Alfacalcidol, Downstream Products: Calcitriol, [[(1a,3b,5E,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3-diyl]bis(oxy)]bis[(1,1-dimethylethyl)dimethylsilane].

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Alfacalcidol (CAS 41294-56-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18947-9 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.