Volinanserin

Also known as: MDL 100907, M100907, (R)-(2,3-dimethoxyphenyl){1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl}methanol, 4-Piperidinemethanol, α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-, (αR)-, (+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol, MDL-100,907, Volinanserin (free base)

Volinanserin (CAS 139290-65-6) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H28FNO3 and a molecular weight of 373.461 g/mol. Key properties include a melting point of 89-91ºC, a boiling point of 499.4±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 255.8±28.7 °C. It is classified under GHS with signal word Warning and hazard statements H400 — Very toxic to aquatic life. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 139290-65-6
Jingsj CID: J-1885-2
Molecular Formula: C₂₂H₂₈FNO₃
Molecular Weight: 373.461 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	89-91ºC
Boiling Point	499.4±45.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	255.8±28.7 °C
Exact Mass	373.205322
PSA	41.93000
LogP	3.56
Vapor Pressure	0.0±1.3 mmHg at 25°C
Refractive Index	1.557
Storage Conditions	2-8℃

GHS Safety & Compliance

Environmental HazardSignal word: Warning

H400 — Very toxic to aquatic life

Activity & Biological Data

Target	Ki: 0.36 nM (5-HT2 receptor)[1]
Additional Information	[1]. Sorensen SM, et al. Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies. J Pharmacol Exp Ther. 1993 Aug;266(2):684-91. [2]. Ardayfio PA, et al. The 5-hydroxytryptamine2A receptor antagonist R-(+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl-4-piperidinemethanol (M100907) attenuates impulsivity after both drug-induced disruption (dizocilpine) and enhancement (antidepressant drugs) of differential-reinforcement-of-low-rate 72-s behavior in the rat. J Pharmacol Exp Ther. 2008 Dec;327(3):891-7.

Target

Ki: 0.36 nM (5-HT2 receptor)[1]

Additional Information

[1]. Sorensen SM, et al. Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies. J Pharmacol Exp Ther. 1993 Aug;266(2):684-91. [2]. Ardayfio PA, et al. The 5-hydroxytryptamine2A receptor antagonist R-(+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl-4-piperidinemethanol (M100907) attenuates impulsivity after both drug-induced disruption (dizocilpine) and enhancement (antidepressant drugs) of differential-reinforcement-of-low-rate 72-s behavior in the rat. J Pharmacol Exp Ther. 2008 Dec;327(3):891-7.

Customs & Trade Information

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Volinanserin?

The CAS number of Volinanserin is 139290-65-6.

What are the molecular formula and molecular weight of Volinanserin?

Volinanserin has molecular formula C22H28FNO3 and molecular weight 373.461 g/mol.

Is Volinanserin hazardous?

Volinanserin has GHS signal word Warning and hazard statements H400 — Very toxic to aquatic life.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Volinanserin (CAS 139290-65-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1885-2 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.