Esculetin
Also known as: 6,7-Dihydroxycoumarin, Aesculetin, Cichorigenin, Esculatin, Esculin aglycon, 6,7-Dihydroxy-2H-chromen-2-one, Cichorigenin, Asculetine, Esculetol, Nsc 26428
Esculetin (CAS 305-01-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C9H6O4 and a molecular weight of 178.141 g/mol. Key properties include a melting point of 271-273 °C(lit.), a boiling point of 469.7±45.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 201.5±22.2 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 305-01-1
- Jingsj CID
- J-18820-5
- Molecular Formula
- C9H6O4
- Molecular Weight
- 178.141 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 271-273 °C(lit.) |
|---|---|
| Boiling Point | 469.7±45.0 °C at 760 mmHg |
| Density | 1.6±0.1 g/cm3 |
| Flash Point | 201.5±22.2 °C |
| Exact Mass | 178.026611 |
| PSA | 70.67000 |
| LogP | 0.98 |
| Vapor Pressure | 0.0±1.2 mmHg at 25°C |
| Refractive Index | 1.689 |
| Storage Conditions | 2-8°C |
| Additional Property | slightly soluble |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | PI3K Akt |
|---|---|
| Additional Information | [1]. Xie C, et al. Esculetin regulates the phenotype switching of airway smooth muscle cells. Phytother Res. 2019 Aug 21. |
Customs & Trade Information
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Esculetin?
The CAS number of Esculetin is 305-01-1.
What are the molecular formula and molecular weight of Esculetin?
Esculetin has molecular formula C9H6O4 and molecular weight 178.141 g/mol.
Is Esculetin hazardous?
Esculetin has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Esculetin?
For Esculetin, Upstream Products: DL-Malic acid, 1,2,4-Triacetoxybenzene, Scopoletin; Downstream Products: 4-Methylesculetin, Scopoletin, Nordalbergin.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Esculetin (CAS 305-01-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18820-5 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.