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1,3-Di-o-tolylguanidine

Also known as: Di-o-tolylguanidine, DOTG, DTG, N,N'-Bis(2-methylphenyl)guanidine, N,N'-Di-o-tolylguanidine, 1,3-Bis(o-tolyl)guanidine, 1,3-Di-o-tolyguanidine, Guanidine, 1,3-di-o-tolyl-, Guanidine, N,N''-bis(2-methylphenyl)-, EINECS 202-577-6, MFCD00008513, 2,2'-Dimethyliminocarbanilide, Accelerator DOTG

1,3-Di-o-tolylguanidine (CAS 97-39-2) is a compound in the Solvents category listed in the Jingsj chemical database. It has the molecular formula C15H17N3 and a molecular weight of 239.32 g/mol. Key properties include a melting point of 176-178 °C(lit.), a boiling point of 396.1±45.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 193.3±28.7 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
97-39-2
Jingsj CID
J-18685-8
Molecular Formula
C15H17N3
Molecular Weight
239.32 g/mol
Category
Solvents
Last updated
8/21/2026

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Physicochemical Properties

Melting Point176-178 °C(lit.)
Boiling Point396.1±45.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point193.3±28.7 °C
Exact Mass239.142242
PSA47.91000
LogP3.77
Vapor Pressure0.0±0.9 mmHg at 25°C
Refractive Index1.585

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed

Activity & Biological Data

TargetSigma receptor[1]
Additional Information[1]. Skuza G, et al. Sigma1 receptor antagonists attenuate antidepressant-like effect induced by co-administration of 1,3 di-o-tolylguanidine (DTG) and memantine in the forced swimming test in rats. Pol J Pharmacol. 2003 Nov-Dec;55(6):1149-52.

Customs & Trade Information

HS Code2925290090
Summary2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 1,3-Di-o-tolylguanidine?

The CAS number of 1,3-Di-o-tolylguanidine is 97-39-2.

What are the molecular formula and molecular weight of 1,3-Di-o-tolylguanidine?

1,3-Di-o-tolylguanidine has molecular formula C15H17N3 and molecular weight 239.32 g/mol.

Is 1,3-Di-o-tolylguanidine hazardous?

1,3-Di-o-tolylguanidine has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of 1,3-Di-o-tolylguanidine?

For 1,3-Di-o-tolylguanidine, Upstream Products: 2-Iodotoluene, 2-Bromotoluene, o-Toluidine; Downstream Products: hydrogen sulfide.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "1,3-Di-o-tolylguanidine (CAS 97-39-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18685-8 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.