Nortadalafil

Also known as: (6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, CS-0823, DeMethyltadalafil, N-DesMethyl Tadalafil, N-Desmethyl Tadalafil, Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-, (6R,12aR)-, Tadalafil Impurity 21, Tadalafil Impurity C, Demethyl Tadalafil

Nortadalafil (CAS 171596-36-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C21H17N3O4 and a molecular weight of 375.377 g/mol. Key properties include a boiling point of 718.6±60.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 388.4±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 171596-36-4
Jingsj CID: J-1866-6
Molecular Formula: C₂₁H₁₇N₃O₄
Molecular Weight: 375.377 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Boiling Point	718.6±60.0 °C at 760 mmHg
Density	1.6±0.1 g/cm3
Flash Point	388.4±32.9 °C
Exact Mass	375.121918
PSA	87.15000
LogP	0.38
Vapor Pressure	0.0±2.3 mmHg at 25°C
Refractive Index	1.772
Storage Conditions	2-8C

Activity & Biological Data

Additional Information	[1]. Beghyn, et al. PDE5 inhibitors: An original access to novel potent arylated analogues of tadalafil. Bioorganic & Medicinal Chemistry Letters (2007), 17(3), 789-792. [2]. Daugan, et al. The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione analogue. Journal of Medicinal Chemistry (2003), 46(21), 4533-4542. [3]. Porst H, et al. Chronic PDE-5 inhibition in patients with erectile dysfunction - a treatment approach using tadalafil once-daily. Expert Opin Pharmacother. 2012 Jul;13(10):1481-94. [4]. Frey MK, Lang I. Tadalafil for the treatment of pulmonary arterial hypertension. Expert Opin Pharmacother. 2012 Apr;13(5):747-55.

Additional Information

[1]. Beghyn, et al. PDE5 inhibitors: An original access to novel potent arylated analogues of tadalafil. Bioorganic & Medicinal Chemistry Letters (2007), 17(3), 789-792. [2]. Daugan, et al. The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione analogue. Journal of Medicinal Chemistry (2003), 46(21), 4533-4542. [3]. Porst H, et al. Chronic PDE-5 inhibition in patients with erectile dysfunction - a treatment approach using tadalafil once-daily. Expert Opin Pharmacother. 2012 Jul;13(10):1481-94. [4]. Frey MK, Lang I. Tadalafil for the treatment of pulmonary arterial hypertension. Expert Opin Pharmacother. 2012 Apr;13(5):747-55.

Frequently Asked Questions

What is the CAS number of Nortadalafil?

The CAS number of Nortadalafil is 171596-36-4.

What are the molecular formula and molecular weight of Nortadalafil?

Nortadalafil has molecular formula C21H17N3O4 and molecular weight 375.377 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Nortadalafil (CAS 171596-36-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1866-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.