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Pyridine-3,5-dicarboxylic acid

Also known as: Dinicotinic acid, 3,5-Pyridinedicarboxylic acid, 5-Carboxynicotinic acid, 3,5-Pyridinedicarboxylate, 5-Pyridinedicarboxylic acid

Pyridine-3,5-dicarboxylic acid (CAS 499-81-0) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C7H5NO4 and a molecular weight of 167.12 g/mol. Key properties include a melting point of >300 °C(lit.), a boiling point of 463.7±30.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 234.3±24.6 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Nov 3, 2026.

CAS No.
499-81-0
Jingsj CID
J-18634-5
Molecular Formula
C7H5NO4
Molecular Weight
167.12 g/mol
Category
Pharma Intermediates
Last updated
11/3/2026

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Physicochemical Properties

Melting Point>300 °C(lit.)
Boiling Point463.7±30.0 °C at 760 mmHg
Density1.6±0.1 g/cm3
Flash Point234.3±24.6 °C
Exact Mass167.021851
PSA87.49000
LogP-0.34
Vapor Pressure0.0±1.2 mmHg at 25°C
Refractive Index1.628
Additional Propertyinsoluble

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Pyridine-3,5-dicarboxylic acid?

The CAS number of Pyridine-3,5-dicarboxylic acid is 499-81-0.

What are the molecular formula and molecular weight of Pyridine-3,5-dicarboxylic acid?

Pyridine-3,5-dicarboxylic acid has molecular formula C7H5NO4 and molecular weight 167.12 g/mol.

Is Pyridine-3,5-dicarboxylic acid hazardous?

Pyridine-3,5-dicarboxylic acid has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Pyridine-3,5-dicarboxylic acid?

For Pyridine-3,5-dicarboxylic acid, Upstream Products: 3,5-Dimethylpyridine, Nicotinic acid, iodomethane; Downstream Products: Methyl 5-aminonicotinate, 5-((tert-Butoxycarbonyl)amino)nicotinic acid, 3,5-Bis(chloromethyl)pyridine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Pyridine-3,5-dicarboxylic acid (CAS 499-81-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18634-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.