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4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoic acid

Also known as: DAMPA, Methotrexate impurity E, Methotrexate EP Impurity E, 4-Amino-4-deoxy-10-methylpteroic acid, 4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoic acid, 4-{[(2,4-diaminopteridin-6-yl)methyl]methylamino}benzoic acid, Benzoic acid, 4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]-, Deoxyaminopteroic acid, Methotrexate metabolite

4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoic acid (CAS 19741-14-1) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C15H15N7O2 and a molecular weight of 325.325 g/mol. Key properties include a melting point of 242 ºC, a boiling point of 689.3±65.0 °C at 760 mmHg, a density of 1.532 and a flash point of 370.7±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
19741-14-1
Jingsj CID
J-18580-8
Molecular Formula
C15H15N7O2
Molecular Weight
325.325 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point242 ºC
Boiling Point689.3±65.0 °C at 760 mmHg
Density1.532
Flash Point370.7±34.3 °C
Exact Mass325.128723
PSA144.14000
LogP1.75
Vapor Pressure0.0±2.3 mmHg at 25°C
Refractive Index1.799
Storage Conditions2-8°C

Activity & Biological Data

Additional Information[1]. Schofield RC, et al. Development and validation of a turbulent flow chromatography and tandem mass spectrometry method for the quantitation of methotrexate and its metabolites 7-hydroxy methotrexate and DAMPA in serum. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 1;1002:169-75.

Customs & Trade Information

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoic acid?

The CAS number of 4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoic acid is 19741-14-1.

What are the molecular formula and molecular weight of 4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoic acid?

4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoic acid has molecular formula C15H15N7O2 and molecular weight 325.325 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoic acid (CAS 19741-14-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18580-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.