(R)-(-)-JQ1

Also known as: (-)-JQ-1, (R)-(-)-JQ1 Enantiomer, (R)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate, tert-Butyl (6R)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate, JQ1, JQ-1, JQ 1

(R)-(-)-JQ1 (CAS 1268524-71-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C23H25ClN4O2S and a molecular weight of 456.988 g/mol. Key properties include a boiling point of 610.4±65.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 322.9±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 1268524-71-5
Jingsj CID: J-1654-6
Molecular Formula: C₂₃H₂₅ClN₄O₂S
Molecular Weight: 456.988 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	610.4±65.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	322.9±34.3 °C
Exact Mass	456.138672
PSA	97.61000
LogP	4.49
Vapor Pressure	0.0±1.7 mmHg at 25°C
Refractive Index	1.657
Storage Conditions	-20°C

Activity & Biological Data

Target	BET bromodomain[1]
Additional Information	[1]. Filippakopoulos, et al. Selective inhibition of BET bromodomains. Nature. 2010 Dec 23;468(7327):1067-73. [2]. Mahe M, et al. An FGFR3/MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers. EMBO Mol Med. 2018 Apr;10(4). pii: e8163.

Frequently Asked Questions

What is the CAS number of (R)-(-)-JQ1?

The CAS number of (R)-(-)-JQ1 is 1268524-71-5.

What are the molecular formula and molecular weight of (R)-(-)-JQ1?

(R)-(-)-JQ1 has molecular formula C23H25ClN4O2S and molecular weight 456.988 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "(R)-(-)-JQ1 (CAS 1268524-71-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1654-6 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.