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Ethyl 4-hydroxy-2-(trifluoromethyl)pyrimidine-5-carboxylate

Also known as: Ethyl 2-trifluoromethyl-4-oxopyrimidine-5-carboxylate, Ethyl 4-hydroxy-2-trifluoromethylpyrimidine-5-carboxylate, 4-Hydroxy-2-trifluoromethyl-pyrimidine-5-carboxylic acid ethyl ester, 5-(Ethoxycarbonyl)-4-hydroxy-2-(trifluoromethyl)pyrimidine, 5-Pyrimidinecarboxylic acid, 1,6-dihydro-6-oxo-2-(trifluoromethyl)-, ethyl ester, Ethyl 6-oxo-2-(trifluoromethyl)-1,6-dihydropyrimidine-5-carboxylate

Ethyl 4-hydroxy-2-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 343-67-9) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C8H7F3N2O3 and a molecular weight of 236.148 g/mol. Key properties include a melting point of 315-316ºC, a boiling point of 220.8±40.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 87.4±27.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
343-67-9
Jingsj CID
J-16444-3
Molecular Formula
C8H7F3N2O3
Molecular Weight
236.148 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point315-316ºC
Boiling Point220.8±40.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point87.4±27.3 °C
Exact Mass236.040878
PSA72.31000
LogP1.26
Vapor Pressure0.1±0.5 mmHg at 25°C
Refractive Index1.475
Storage Conditions2-8°C

Customs & Trade Information

HS Code2933599090
Summary2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Ethyl 4-hydroxy-2-(trifluoromethyl)pyrimidine-5-carboxylate?

The CAS number of Ethyl 4-hydroxy-2-(trifluoromethyl)pyrimidine-5-carboxylate is 343-67-9.

What are the molecular formula and molecular weight of Ethyl 4-hydroxy-2-(trifluoromethyl)pyrimidine-5-carboxylate?

Ethyl 4-hydroxy-2-(trifluoromethyl)pyrimidine-5-carboxylate has molecular formula C8H7F3N2O3 and molecular weight 236.148 g/mol.

What are the upstream and downstream products of Ethyl 4-hydroxy-2-(trifluoromethyl)pyrimidine-5-carboxylate?

For Ethyl 4-hydroxy-2-(trifluoromethyl)pyrimidine-5-carboxylate, Upstream Products: Water, Diethyl ethoxymethylenemalonate, Trifluoroacetamidine; Downstream Products: 2-(trifluoromethyl)pyrimidine-5-carbaldehyde, Ethyl 2-(trifluoromethyl)pyrimidine-5-carboxylate, Ethyl 4-chloro-2-(trifluoromethyl)pyrimidine-5-carboxylate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Ethyl 4-hydroxy-2-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 343-67-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-16444-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.