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Tetrahydroalstonine

Also known as: (-)-Tetrahydroalstonine, Alstonine, 3,4,5,6-tetrahydro-, (3α)-, 3α,4,5,6-Tetrahydroalstonine, NSC 72115, methyl (19α,20α)-16,17-didehydro-19-methyl-18-oxayohimban-16-carboxylate, (20α)-16,17-Didehydro-19α-methyl-18-oxayohimban-16-carboxylic acid methyl ester

Tetrahydroalstonine (CAS 6474-90-4) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C21H24N2O3 and a molecular weight of 352.427 g/mol. Key properties include a melting point of 227ºC, a boiling point of 524.0±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 270.7±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
6474-90-4
Jingsj CID
J-1601-3
Molecular Formula
C21H24N2O3
Molecular Weight
352.427 g/mol
Category
Organic Bases
Last updated
8/21/2026

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Physicochemical Properties

Melting Point227ºC
Boiling Point524.0±50.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point270.7±30.1 °C
Exact Mass352.178680
PSA54.56000
LogP2.88
Vapor Pressure0.0±1.4 mmHg at 25°C
Refractive Index1.656
Storage Conditions-20°C

Activity & Biological Data

Additional Information[1]. Malik S, et al. Tetrahydroalstonine from Fruits of Rhazya stricta. Planta Med. 1984 Jun;50(3):283. [2]. Roquebert J, et al. Inhibition of the alpha 1 and alpha 2-adrenoceptor-mediated pressor response in pithed rats by raubasine, tetrahydroalstonine and akuammigine. Eur J Pharmacol. 1984 Oct 30;106(1):203-5.https://www.ncbi.nlm.nih.gov/pubmed/6099269

Frequently Asked Questions

What is the CAS number of Tetrahydroalstonine?

The CAS number of Tetrahydroalstonine is 6474-90-4.

What are the molecular formula and molecular weight of Tetrahydroalstonine?

Tetrahydroalstonine has molecular formula C21H24N2O3 and molecular weight 352.427 g/mol.

What are the upstream and downstream products of Tetrahydroalstonine?

For Tetrahydroalstonine, Upstream Products: tryptamine, Dimethyl sulfoxide, Secologanin.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Tetrahydroalstonine (CAS 6474-90-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1601-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.