Endoxifen
Also known as: (Z)-Endoxifen, (Z)-4-Hydroxy-N-desmethyl Tamoxifen, 4-Hydroxy-N-desmethyltamoxifen, 4-[(1Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol, Phenol, 4-[(1Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]-, UNII-46AF8680RC, Z-Endoxifen, 4OHNDtam
Endoxifen (CAS 112093-28-4) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C25H27NO2 and a molecular weight of 373.48700 g/mol. Key properties include a melting point of 127-129°C, a boiling point of 519.327ºC at 760 mmHg, a density of 1.099g/cm3 and a flash point of 267.88ºC. It is classified under GHS with signal word Warning and hazard statements H400 — Very toxic to aquatic life. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 112093-28-4
- Jingsj CID
- J-1596-1
- Molecular Formula
- C25H27NO2
- Molecular Weight
- 373.48700 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 127-129°C |
|---|---|
| Boiling Point | 519.327ºC at 760 mmHg |
| Density | 1.099g/cm3 |
| Flash Point | 267.88ºC |
| Exact Mass | 373.20400 |
| PSA | 41.49000 |
| LogP | 5.75040 |
| Vapor Pressure | 0mmHg at 25°C |
| Refractive Index | 1.599 |
| Storage Conditions | Amber Vial, -86°C Freezer, Under Inert Atmosphere |
GHS Safety & Compliance
- H400 — Very toxic to aquatic life
Activity & Biological Data
| Additional Information | [1]. Chae YJ, et al. Endoxifen, the active metabolite of tamoxifen, inhibits cloned hERG potassium channels. Eur J Pharmacol. 2015 Apr 5;752:1-7. [2]. Wu X, et al. Estrogen receptor-beta sensitizes breast cancer cells to the anti-estrogenic actions of endoxifen. Breast Cancer Res. 2011 Mar 10;13(2):R27. |
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Frequently Asked Questions
What is the CAS number of Endoxifen?
The CAS number of Endoxifen is 112093-28-4.
What are the molecular formula and molecular weight of Endoxifen?
Endoxifen has molecular formula C25H27NO2 and molecular weight 373.48700 g/mol.
Is Endoxifen hazardous?
Endoxifen has GHS signal word Warning and hazard statements H400 — Very toxic to aquatic life.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Endoxifen (CAS 112093-28-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1596-1 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.